Results 81 to 90 of about 43,676 (287)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Model tests on 3D soil arching in pile-supported embankments with and without geotextile

Case Studies in Construction Materials
Compared to traditional soil improvement methods such as preloading, vertical drains, or grouting injection, et al., pile-supported reinforced embankments are increasing widely employed in the construction of highways on soft soils.
Weiping Cao, Zedong Xie, Yaxin Yue, Min Zhao, Qing Li, Weiwei Hu   +5 more
doaj   +1 more source

Effect of blast induced rock fragmentation and muckpile angle on excavator performance in surface mines [PDF]

, 2019
Purpose. A fit excavator in a surface mine gives a trouble free production. To maintain the condition and safety of an excavator, proper sizes of rock fragmentation and muckpile parameters are crucial besides its maintenance.
Choudhary, B.S.
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Vertical bearing capacity of a pile-liquefiable sandy soil foundation under horizontal seismic force.

PLoS ONE, 2020
In this study, research on a pile group system was conducted using shaking table tests under four working conditions: a natural foundation and pile-spacing conditions of 3D, 3.5D, and 4D (D is the diameter of the pile).
Huang Zhanfang, Bai Xiaohong, Yin Chao, Wang Yanping   +3 more
doaj   +1 more source

Effect of Spacing and Cross-Sectional Shape on Piled Raft System Subjected to Lateral Cyclic Loading

Diyala Journal of Engineering Sciences, 2020
Piled raft foundations usually supporting bridge piers, offshore platforms, marine structures and others are required to resist not only static loading, but also lateral cyclic loading that developed from different sources of loadings.
Wafaa A.Saleh
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Experimental Research on Pile-Soil Stress Ratio of Rigid Pile Composite Foundation in Shallow-Buried Rock and Soft Soil [PDF]

长江科学院院报
[Objective] Pile-soil stress ratio is a key parameter in the design of rigid pile composite foundations for shallow-buried rock and soft soil foundations, but the rules governing its value and influencing factors remain unclear.
REN Jia-li, JIANG Ji-wei, HU Sheng-gang, CHEN Hang, YE Chen-hui
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source