Results 71 to 80 of about 285,872 (230)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Background Hemorrhoids are vascular structures in the anal canal which are seldom used to evaluate vascular diseases. Cigarette smoking is well-known to cause both arterial and venous vascular injuries.
Savitha V. Nagaraj +2 more
doaj +1 more source
Pile tunnel interaction: literature review and data analysis [PDF]
The underground space of densely populated cities contains deep foundations and tunnels. Considering the possibility that a new tunnel can be built close to existing piles it is necessary to assess the possible effects of that interaction.
Bezuijen, Adam +1 more
core
Avalanche statistics of sand heaps
Large scale computer simulations are presented to investigate the avalanche statistics of sand piles using molecular dynamics. We could show that different methods of measurement lead to contradicting conclusions, presumably due to avalanches not ...
H. M. Jaeger +12 more
core +2 more sources
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Introduction. A characteristic feature of works on constructing the underground part of buildings or structures in the conditions of St. Petersburg is the significant thickness of weak clay soils.
A. B. Ponomarev +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Aims. The purpose of this work is to justify the reliability of the developed models of pile foundations on the data of field observers and to demonstrate the feasibility of using pile foundations to increase the stability and bearing capacity of the NPP
Akop E. Sargsyan, Elena G. Gukova
doaj +1 more source
Top Bar Effects in Prestressed Concrete Piles [PDF]
The top bar effect in reinforced concrete is a widely recognized phenomenon. Currently, the ACI Building Code prescribes a 30% increase in the development length of top cast reinforcing bars.
Harries, Kent A. +3 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

