Results 81 to 90 of about 80,000 (303)

Interaction of piled foundation with a rupturing normal fault [PDF]

open access: yes, 2013
Post-seismic observations in the 1999 Kocaeli earthquake in Turkey have indicated that piled foundations may be less suitable than stiff mat foundations in defending a structure against a major normal fault rupturing underneath.
Kourkoulis, R.   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Numerical Investigation of the Effect of Geocell-Reinforced Cushion on Load Distribution and Settlement Reduction in Unconnected Piled Raft Foundations

open access: yesFirat University Journal of Experimental and Computational Engineering
The effect of geocell-reinforced cushion on load distribution and settlement reduction in unconnected piled raft foundations was investigated. Modeling and analysis of various scenarios were carried out using Abaqus software. In this research, a total of
Mojtaba Pourgholamali, Farzin Asgharpour
doaj   +1 more source

The behaviour of laterally loaded two-pile groups [PDF]

open access: yes, 1992
The response of piles and two-pile groups to lateral loading has been studied by field tests and computationally. Due to the lack of field test data and because of uncertainty concerning the pile/soil system it has been suggested that further ...
Arta, M.R., Arta, Mahmood Reza
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The bearing capacity and settlement of gravel piles in clay [PDF]

open access: yes, 1980
Includes bibliography.The writer has been interested in the subject of gravel piles for a number of years and has been suprised at the lack of rational design methods.
Jones, David Leonard
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Model test on the load bearing mechanism of inclined pile-sheet retaining wall

open access: yes矿业科学学报
The inclined pile-sheet retaining wall differs from the traditional pile-sheet retaining wall in the stress and distribution of earth pressure behind the wall because of the inclination of the retaining plates. Its mechanism is unclear while its existing
GE Sha   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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