Results 31 to 40 of about 29,113 (202)

FimH and Type 1 Pili Mediated Tumor Cell Cytotoxicity by Uropathogenic Escherichia coli In Vitro

Pathogens, 2023
Uropathogenic Escherichia coli express hairlike proteinaceous surface projections, known as chaperone–usher pathway (CUP) pili. Type 1 pili are CUP pili with well-established pathogenic properties. The FimH adhesin subunit of type 1 pili plays a key role
Shelly Roselyn Van Eyssen, Anastasia Samarkina, Ovgu Isbilen, Merve Suzan Zeden, Ender Volkan   +4 more
doaj   +1 more source

Status of Management Practices of Business Enterprise in Buhi, Camarines Sur

Journal of Education, Management and Development Studies
Management practices are significant in the development of business enterprises in Buhi, Camarines Sur. It is important to focus form the internal aspects to understand the different management practices that help the institution to remain strong and ...
David Escalante, Michelle B. Maligang, Janne Cielo, Leizl Espinas, Marites Dumalagan-Arines   +4 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Sculpting the Bacterial O-Glycoproteome: Functional Analyses of Orthologous Oligosaccharyltransferases with Diverse Targeting Specificities

mBio, 2022
Protein glycosylation systems are widely recognized in bacteria, including members of the genus Neisseria. In most bacterial species, the molecular mechanisms and evolutionary contexts underpinning target protein selection and the glycan repertoire ...
Chris Hadjineophytou, Jan Haug Anonsen, Tina Svingerud, Tatum D. Mortimer, Yonatan H. Grad, Nichollas E. Scott, Michael Koomey   +6 more
doaj   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

Architecture of the biofilm-associated archaic Chaperone-Usher pilus CupE from Pseudomonas aeruginosa.

PLoS Pathogens, 2023
Chaperone-Usher Pathway (CUP) pili are major adhesins in Gram-negative bacteria, mediating bacterial adherence to biotic and abiotic surfaces. While classical CUP pili have been extensively characterized, little is known about so-called archaic CUP pili,
Jan Böhning, Adrian W Dobbelstein, Nina Sulkowski, Kira Eilers, Andriko von Kügelgen, Abul K Tarafder, Sew-Yeu Peak-Chew, Mark Skehel, Vikram Alva, Alain Filloux, Tanmay A M Bharat   +10 more
doaj   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Phototaxis in Cyanobacteria: From Mutants to Models of Collective Behavior

mBio, 2021
Cyanobacteria rely on photosynthesis, and thus have evolved complex responses to light. These include phototaxis, the ability of cells to sense light direction and move towards or away from it.
Shakti N. Menon, P. Varuni, Freddy Bunbury, Devaki Bhaya, Gautam I. Menon   +4 more
doaj   +1 more source

Influence of the pili of Lacticaseibacillus rhamnosus GG on its encapsulation and survival in mixed protein-starch gels assembled by in situ fermentation

Applied and Environmental Microbiology
Preserving the viability of probiotics during storage and gastrointestinal digestion poses a significant challenge in the development of effective probiotic formulations.
Tana Hernandez-Barrueta, Silvia Lorena Amaya-Llano, Nitin Nitin   +2 more
doaj   +1 more source

Lectins of Mycobacterium tuberculosis – rarely studied proteins

Beilstein Journal of Organic Chemistry, 2019
The importance of bacterial lectins for adhesion, pathogenicity, and biofilm formation is well established for many Gram-positive and Gram-negative bacteria.
Katharina Kolbe, Sri Kumar Veleti, Norbert Reiling, Thisbe K. Lindhorst   +3 more
doaj   +1 more source