Results 51 to 60 of about 113,687 (274)

FimH and Type 1 Pili Mediated Tumor Cell Cytotoxicity by Uropathogenic Escherichia coli In Vitro

Pathogens, 2023
Uropathogenic Escherichia coli express hairlike proteinaceous surface projections, known as chaperone–usher pathway (CUP) pili. Type 1 pili are CUP pili with well-established pathogenic properties. The FimH adhesin subunit of type 1 pili plays a key role
Shelly Roselyn Van Eyssen, Anastasia Samarkina, Ovgu Isbilen, Merve Suzan Zeden, Ender Volkan   +4 more
doaj   +1 more source

Mechanisms of Bacterial Extracellular Electron Exchange. [PDF]

, 2016
The biochemical mechanisms by which microbes interact with extracellular soluble metal ions and insoluble redox-active minerals have been the focus of intense research over the last three decades. The process presents two challenges to the microorganism;
Butt, Julea N., Clarke, Thomas A., Edwards, Marcus J., Gomez-Perez, Laura, Richardson, David J., White, Gaye F.   +5 more
core   +1 more source

Structure and function of minor pilins of type IV pili

Medical Microbiology and Immmunology, 2019
Type IV pili are versatile and highly flexible fibers formed on the surface of many Gram-negative and Gram-positive bacteria. Virulence and infection rate of several pathogenic bacteria, such as Neisseria meningitidis and Pseudomonas aeruginosa , are ...
Theis Jacobsen, B. Bardiaux, O. Francetic, N. Izadi-Pruneyre, M. Nilges   +4 more
semanticscholar   +1 more source

Status of Management Practices of Business Enterprise in Buhi, Camarines Sur

Journal of Education, Management and Development Studies
Management practices are significant in the development of business enterprises in Buhi, Camarines Sur. It is important to focus form the internal aspects to understand the different management practices that help the institution to remain strong and ...
David Escalante, Michelle B. Maligang, Janne Cielo, Leizl Espinas, Marites Dumalagan-Arines   +4 more
doaj   +1 more source

Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili. [PDF]

PLoS ONE, 2016
Mapping of the microbial molecules underlying microbiota-host interactions is key to understand how microbiota preserve mucosal homeostasis. A pivotal family of such bacterial molecules are pili.
Hanne L P Tytgat, Nienke H van Teijlingen, Ruby May A Sullan, François P Douillard, Pia Rasinkangas, Marcel Messing, Justus Reunanen, Reetta Satokari, Jos Vanderleyden, Yves F Dufrêne, Teunis B H Geijtenbeek, Willem M de Vos, Sarah Lebeer   +12 more
doaj   +1 more source

DNA-uptake pili of Vibrio cholerae are required for chitin colonisation and capable of kin recognition via sequence-specific self-interaction

Nature Microbiology, 2019
How bacteria colonize surfaces and how they distinguish the individuals around them are fundamental biological questions. Type IV pili are a widespread and multipurpose class of cell surface polymers.
David. W. Adams, Sandrine Stutzmann, Candice Stoudmann, Melanie Blokesch   +3 more
semanticscholar   +1 more source

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics [PDF]

, 2008
Adhesive multi-subunit fibres are assembled on the surface of many pathogenic bacteria via the chaperone-usher pathway. In the periplasm, a chaperone donates a β-strand to a pilus subunit to complement its incomplete immunoglobulin-like fold.
Ashcroft, A.E., Paci, E., Radford, S.E., Rose, R.J., Waksman, G., Welsh, T.S.   +5 more
core   +1 more source

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection [PDF]

, 2018
Significance The emergence of multidrug-resistant bacteria, including uropathogenic Escherichia coli (UPEC), makes the development of targeted antivirulence therapeutics a critical focus of research.
Chugani, Ryan, Conover, Matt S., Hibbing, Michael E., Hultgren, Scott J., Janetka, James W., Kalas, Vasilios, Maddirala, Amarendar Reddy, Mydock-McGrane, Laurel K., Pinkner, Jerome S.   +8 more
core   +2 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Adhesive Pili in UTI Pathogenesis and Drug Development

Pathogens, 2016
Urinary tract infections (UTIs) are one of the most common bacterial infections, affecting 150 million people each year worldwide. High recurrence rates and increasing antimicrobial resistance among uropathogens are making it imperative to develop ...
Caitlin N. Spaulding, Scott J. Hultgren
doaj   +1 more source