Results 1 to 10 of about 414,611 (257)

The original anticonvulsant meta-Cl-benzhydrylurea (m-CL-BHM) induces of the liver monooxygenase system and stimulates the neuroimmune response in behavioral disorders of alcoholic origin

open access: yesEuropean Psychiatry, 2022
Introduction The anticonvulsant m-Cl-BHM is promising for the pathogenetically directed thrapy does not cause negative effects. Objectives Investigation of the effect of m-Сl-BHM on “immunochemical homeostasis” in rats with experimental alcoholism ...
Т. Shushpanova   +12 more
doaj   +1 more source

Pharmacogenetic Guidelines for Psychotropic Drugs: Optimizing Prescriptions in Clinical Practice

open access: yesPharmaceutics, 2023
The modalities for prescribing a psychotropic (dose and choice of molecule) are currently unsatisfactory, which can lead to a lack of efficacy of the treatment associated with prolonged exposure of the patient to the symptoms of his or her illness and ...
Antoine Baldacci   +8 more
doaj   +1 more source

Specialization of the Reiterated Copies of the Heterodimeric Integration Host Factor Genes in Geobacter sulfurreducens

open access: yesFrontiers in Microbiology, 2021
Integration host factor (IHF) is a widely distributed small heterodimeric protein member of the bacterial Nucleoid-Associated Proteins (NAPs), implicated in multiple DNA regulatory processes.
Angel Andrade   +8 more
doaj   +1 more source

Age-related modifications in CYP-dependent drug metabolism: role of stress

open access: yesFrontiers in Endocrinology, 2023
Accumulating clinical evidence indicates extensive inter-individual variations in the effectiveness and adverse effects of standard treatment protocols, which are largely attributed to the multifactorial regulation of the hepatic CYP-dependent drug ...
Maria Konstandi, Elizabeth O. Johnson
doaj   +1 more source

Exploring oxidative stress pathways in Geobacter sulfurreducens: the redox network between MacA peroxidase and triheme periplasmic cytochromes

open access: yesFrontiers in Microbiology, 2023
The recent reclassification of the strict anaerobe Geobacter sulfurreducens bacterium as aerotolerant brought attention for oxidative stress protection pathways.
Pilar C. Portela   +9 more
doaj   +1 more source

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products

open access: yesJournal of Mind and Medical Sciences, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Nicolae Bacinschi   +6 more
doaj   +1 more source

Radiothermometric Study of the Effect of Amino Acid Mutation on the Characteristics of the Enzymatic System

open access: yesDiagnostics, 2022
The radiothermometry (RTM) study of a cytochrome-containing system (CYP102 A1) has been conducted in order to demonstrate the applicability of RTM for monitoring changes in the functional activity of an enzyme in case of its point mutation. The study has
Yuri D. Ivanov   +9 more
doaj   +1 more source

Geobacter Protein Nanowires

open access: yesFrontiers in Microbiology, 2019
The study of electrically conductive protein nanowires in Geobacter sulfurreducens has led to new concepts for long-range extracellular electron transport, as well as for the development of sustainable conductive materials and electronic devices with ...
Derek R. Lovley, David J. F. Walker
doaj   +1 more source

Redox-Regulation of α-Globin in Vascular Physiology

open access: yesAntioxidants, 2022
Interest in the structure, function, and evolutionary relations of circulating and intracellular globins dates back more than 60 years to the first determination of the three-dimensional structure of these proteins.
Laurent Kiger   +7 more
doaj   +1 more source

Gibberellin and auxin production by plant root-fungi and their biosynthesis under salinity-calcium interaction

open access: yesPlant, Soil and Environment, 2002
Rhizosphere and rhizoplane of fababean (Vicia faba), melochia (Corchorus olitorius), sesame (Sesamum indicum) and soyabean (Glycine max) plants are inhabited with fungi, mostly Aspergillus flavus, A. niger, Fusarium oxysporum, Penicillium corylophilum, P.
H.A.H. Hasan
doaj   +1 more source

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