Results 11 to 20 of about 499,967 (230)

The original anticonvulsant meta-Cl-benzhydrylurea (m-CL-BHM) induces of the liver monooxygenase system and stimulates the neuroimmune response in behavioral disorders of alcoholic origin

open access: yesEuropean Psychiatry, 2022
Introduction The anticonvulsant m-Cl-BHM is promising for the pathogenetically directed thrapy does not cause negative effects. Objectives Investigation of the effect of m-Сl-BHM on “immunochemical homeostasis” in rats with experimental alcoholism ...
Т. Shushpanova   +12 more
doaj   +1 more source

Pharmacogenetic Guidelines for Psychotropic Drugs: Optimizing Prescriptions in Clinical Practice

open access: yesPharmaceutics, 2023
The modalities for prescribing a psychotropic (dose and choice of molecule) are currently unsatisfactory, which can lead to a lack of efficacy of the treatment associated with prolonged exposure of the patient to the symptoms of his or her illness and ...
Antoine Baldacci   +8 more
doaj   +1 more source

Bespoke Biomolecular Wires for Transmembrane Electron Transfer: Spontaneous Assembly of a Functionalized Multiheme Electron Conduit

open access: yesFrontiers in Microbiology, 2021
Shewanella oneidensis exchanges electrons between cellular metabolism and external redox partners in a process that attracts much attention for production of green electricity (microbial fuel cells) and chemicals (microbial electrosynthesis).
Samuel E. H. Piper   +8 more
doaj   +1 more source

Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP

open access: yesMolecules, 2023
Cytochrome P450 OleP catalytic activity is strongly influenced by its structural dynamic conformational behavior. Here, we combine equilibrium-binding experiments with all-atom molecular dynamics simulations to clarify how different environments affect ...
Maria Laura De Sciscio   +11 more
doaj   +1 more source

Cytochrome and cytochrome oxidase [PDF]

open access: yesProceedings of the Royal Society of London. Series B - Biological Sciences, 1939
Abstract It was previously shown that the addition of cytochrome c to a heart-muscle preparation greatly increases its power of catalysing the oxidation of such substances as p-phenylene diamine, hydroquinone, cysteine and ascorbic acid.
David Keilin   +2 more
openaire   +1 more source

Genome-Wide Comparative Profiles of Triterpenoid Biosynthesis Genes in Ginseng and Pseudo Ginseng Medicinal Plants

open access: yesLife, 2023
Saponin-rich medicinal plants, particularly ginseng and Pseudo ginseng, are valuable in traditional medical practice due to the presence of different saponins.
Jing Lu
doaj   +1 more source

Cytochromes P450 [PDF]

open access: yesThe Arabidopsis Book, 2002
There are 272 cytochrome P450 genes (including 26 pseudogenes) in the Arabidopsis genome. P450s thus form one of the largest families of proteins in higher plants. This explosion of the P450 family is thought to have occurred via gene duplication and conversion, and to result from the need of sessile plants to adapt to a harsh environment and to ...
Danièle, Werck-Reichhart   +2 more
openaire   +2 more sources

Lack of salidroside impact on selected cytochromes encoding genes transcription in the liver of ethanol induced rats

open access: yesHerba Polonica, 2021
Introduction: The molecular basis of in vivo metabolism of selected representatives of phenylethanoids in the presence of ethanol has not been fully elucidated.
Kujawski Radosław   +9 more
doaj   +1 more source

Pitavastatin: focus on safety and drug interactions

open access: yesКардиоСоматика, 2021
Pitavastatin is a drug from the group of HMG-CoA reductase inhibitors, which has good lipid-lowering efficacy and has no significant effect on the risk of diabetes mellitus.
Larisa O. Minushkina   +1 more
doaj   +1 more source

Geobacter Protein Nanowires

open access: yesFrontiers in Microbiology, 2019
The study of electrically conductive protein nanowires in Geobacter sulfurreducens has led to new concepts for long-range extracellular electron transport, as well as for the development of sustainable conductive materials and electronic devices with ...
Derek R. Lovley, David J. F. Walker
doaj   +1 more source

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