Spontaneous Seizure Outcomes in Mice Using an Improved Version of the Pilocarpine Model of Temporal Lobe Epilepsy. [PDF]
Gaykema RP +9 more
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Inhibitory effect of the methanol extract of Clerodendrum volubile Linn. on carbon tetrachloride-induced early hepatic fibrogenesis: in silico and in vivo study. [PDF]
Oyeyemi IT +5 more
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Dynamic astrocytic complement C3 activation in the epileptic hippocampus. [PDF]
Jiang M, Romagnolo A, Aronica E, Wang Y.
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Pilocarpine 1.25% efficacy for management of uncorrected presbyopia (PILE-UP study). [PDF]
Saxena R +6 more
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Machine-Learning-Based Automated Schlemm's Canal Volumetric Segmentation for Optical Coherence Tomography. [PDF]
Fang R +6 more
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Swish!-All I Hear is Net-Perineuronal Net That is! [PDF]
Stafstrom CE.
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A New Toolbox to Label Zinc-MTF1 Responsive Neuronal Populations Unravels Cellular Congruence between MTF1 Responses and T-type Calcium Channelopathies in an Experimental Model of Epilepsy. [PDF]
Meconi A +7 more
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Pilocarpine is a direct-acting parasympathomimetic agent exerting a broad spectrum of pharmacological actions mediated through muscarinic acetylcholine receptors. It is non-selective for the various muscarinic receptors and does not stimulate nicotinic acetylcholine receptors.
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Serum Pilocarpine Esterase Activity and Response to Oral Pilocarpine
Biochemical and Molecular Medicine, 1996Pilocarpine is used orally to treat xerostomia but patients vary widely in their response and ability to tolerate this drug. To elucidate the potential pharmacokinetic contribution of serum to this variability, the enzymatic hydrolysis of pilocarpine in human serum in vitro was investigated using a stability indicating HPLC assay.
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