Results 111 to 120 of about 34,054 (232)
Epilepsia, Volume 67, Issue 5, Page 2572-2584, May 2026.Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz +10 more
wiley +1 more source
Frontiers in Neurology, 2019 The maintenance of blood-brain barrier (BBB) integrity is essential for providing a suitable environment for nervous tissue function. BBB disruption is involved in many central nervous system diseases, including epilepsy.
Natália Ferreira Mendes +9 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aims Xerostomia, or dry mouth, significantly impairs quality of life and oral health, particularly in patients subjected to radiation therapy or suffering from systemic disorders. This narrative review summarizes the current evidence on the efficacy and safety of gene therapy interventions for xerostomia, exploring innovative ...
Muhammad Usman Bilal +6 more
wiley +1 more source
On the action of pilocarpine [PDF]
The Journal of Physiology, 1927 T B, Heaton, M H, Mackeith
openaire +2 more sources
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 10, Page 3786-3801, 15 May 2026.Abstract figure legend Local sweating response and sweating onset of boys, girls, adult females and adult males during treadmill walking at a fixed metabolic heat production per body surface area (300 W·m−2) in warm and hot environments. Bayesian hierarchical modelling showed no meaningful sex or age differences in local sweating responses or onset ...
Thomas H. Topham +7 more
wiley +1 more source
The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]
, 2011 Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman +8 more
core +1 more source
Neuronal oxidative injury in the development of the epileptic disease : a potential target for novel therapeutic approaches [PDF]
, 2011 Epileptic diseases affect about 50 million people in the world and approximately 30% of patients diagnosed with epilepsy are unresponsive to current medications.
Maio, Roberto di
core
Acta Ophthalmologica, Volume 104, Issue 3, Page e356-e359, May 2026.
Michael Hafner +6 more
wiley +1 more source
Siriraj Medical JournalObjective: This study aimed to assess and compare the effectiveness and side effects of various concentrations of pilocarpine eye drops (1.5%, 1.25%, and 1%), with and without 0.1% brimonidine, in treating presbyopia, specifically in a Thai population.
Thammanoon Surachatkumtonekul +6 more
doaj