Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
Understanding Partisan Bias in Judgments of Misinformation: Identity Protection Versus Differential Knowledge. [PDF]
Hubeny TJ, Nahon LS, Gawronski B.
europepmc +1 more source
China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu +3 more
wiley +1 more source
Pilot randomized study of three digital models to train opioid use disorder counselors in community reinforcement and family training. [PDF]
Macky J +10 more
europepmc +1 more source
Impact of TiLT assignments in a college of pharmacy: A pilot study
Sylvia Rogers +2 more
openaire +1 more source
A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang +6 more
wiley +1 more source
Does exposure within an experiment affect the influence of familiar parts versus wholes on figure assignment? [PDF]
Flowers CS, Peterson MA.
europepmc +1 more source
Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials
This study presents a modular kirigami metamaterial framework enabling programmable multistability and sequential 4D actuation. By coupling geometry‐controlled multistability with material‐dependent recovery kinetics, spatiotemporal deformation can be precisely programmed.
Eui‐Hyun Kim +3 more
wiley +1 more source
Collocated mixed reality for basic life support training in medical students: a randomised pilot feasibility trial. [PDF]
Maiershon D +11 more
europepmc +1 more source

