Results 41 to 50 of about 9,874,780 (237)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conditioning-Centric Design of RIS-Assisted Uplink Channel Estimation Under Heterogeneous Propagation

open access: yesIEEE Open Journal of the Communications Society
Reconfigurable intelligent surfaces (RIS) allow programmable wireless propagation but add intrinsic problems in the estimation of the uplink channel because of high-dimensional cascaded channels, limited pilot budgets, heterogeneous propagation, and ...
Shweta Singh   +3 more
doaj   +1 more source

A Novel Method of Trajectory Optimization for Underwater Gliders Based on Dynamic Identification

open access: yesJournal of Marine Science and Engineering, 2022
For underwater gliders (UGs), high trajectory accuracy is an important factor in improving the observation of ocean phenomena. In this paper, a novel method of trajectory optimization is proposed to increase the trajectory accuracy of UGs, which is ...
Ming Yang   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Pilot Rock Notice of Adopted Amendment (2007-05-07)

open access: yes, 2007
9 pp. Adopted 2007-05-07. Department of Land Conservation and Development Notice of Adopted AmendmentWe annexed 445 acres into the City of Pilot Rock.
Pilot Rock (Or.)
core   +1 more source

Channel estimation of UFMC system in multipath channel

open access: yesDianxin kexue, 2018
As a candidate waveform of 5G,universal filter multi-carrier (UFMC) technology could inhibit out-of-band radiation,achieve loose synchronization and well support the short bursts of things in the transmission.However,in the UFMC transmission without ...
Xiang YU, Yanni GAO, Sirui DUAN
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Requests from Companies and Requirements for Design Education in Brazil: where do they meet? [PDF]

open access: yes, 2018
In this paper, we study what companies request from applicants for graphic design positions in Brazil. Based on a document analysis of 371 job advertisements, we uncover 35 different types of requests which we structure in terms of (1) Design ...
Person, Oscar   +10 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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