Results 51 to 60 of about 10,290,974 (193)

The Value of Design-led Innovation in Chinese SMEs [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThis paper focuses on understanding the role and use of design-led innovation in Chinese SMEs. The insights were gained by undertaking a pilot study, based on an applied developmental research approach involving ...
Bolton, S.
core   +3 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mechanical design BLAZE pilot plant components

open access: yes, 2023
Mechanical design BLAZE pilot plant components related to WP5, D5.
valerio corradetti   +3 more
core   +2 more sources

Pilot design for underwater MIMO cosparse channel estimation based on compressed sensing

open access: yesInternational Journal of Distributed Sensor Networks, 2021
In multiple-input multiple-output–orthogonal frequency-division multiplexing underwater acoustic communication systems, the correlation of the sampling matrix is the key of the channel estimation algorithm based on compressed sensing. To reduce the cross-
Yun Li   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Company [PDF]

open access: yes, 2018
Poem by Nathan Walker published in 'The Queer Anthology of Rage' by Pilot ...
Walker, Nathan
core   +1 more source

Signal Design for Communication Centric ISAC: State of Art and Future Aspects

open access: yesLeida xuebao
Integrated Sensing And Communications (ISAC), a key technology for 6G networks, has attracted extensive attention from both academia and industry. Leveraging the widespread deployment of communication infrastructures, the integration of sensing functions
Aimin TANG   +8 more
doaj   +1 more source

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