Results 41 to 50 of about 144,847 (303)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

A novel blood based triage test for colorectal cancer in primary care: a pilot study

open access: yesBJGP Open, 2023
Background: The majority of colorectal cancers (CRCs) are detected after symptomatic presentation to primary care. Given the shared symptoms of CRC and benign disorders, it is challenging to manage the risk of missed diagnosis.
Cerys Jenkins   +18 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evaluation of BT Telecare Pilot Project [PDF]

open access: yes, 2010
Telecare can be defined as a mechanism for providing health and social services 'at a distance' - usually into the user's home - through the use of information and communication technologies.
Crump, N
core  

Who benefits from rural development projects? a case study of the komati pilot project, Swaziland

open access: yes, 2001
The Komati Pilot Project has been developed by Swaziland's Ministry of Agriculture and Co-operatives to act as a learning experience prior to the major expansion of smallholder farming on the Maguga and proposed Bovane irrigation projects. Because of the
Terry, A. K.
core   +1 more source

A Pilot Study of Endoscopic Submucosal Dissection Using an Endoscopic Assistive Robot in a Porcine Stomach Model

open access: yesGut and Liver, 2019
Background/AimsEndoscopic assistive devices have been developed to reduce the complexity and improve the safety of surgeries involving the use of endoscopes.
Byung Gon Kim   +8 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

City of Pilot Rock transportation system plan : Final report [PDF]

open access: yes, 2001
100 pp. Maps and figures included. Published June 2001. Received from ODOT January 2, 2007.The City of Pilot Rock Transportation System Plan (TSP) guides the management of existing transportation facilities and the design and implementation of future ...
David Evans and Associates   +1 more
core  

ZEN PILOT PROJECTS. Mapping of the pilot projects within the research centre on ZERO emission neighbourhoods in smart cities [PDF]

open access: yes, 2018
This report on the pilot projects of the Research Centre on Zero Emission Neighbourhoods in Smart Cities (ZEN Centre) will give the reader an overview of eight pilot projects of the Centre, focusing on the challenges to develop or transform the pilot ...
Andresen, Inger, Baer, Daniela
core   +2 more sources

A modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT

open access: yesHealth Technology Assessment, 2022
Background: Looked-after children are at risk of suboptimal attachment patterns and reactive attachment disorder. However, access to interventions varies widely and there are no evidence-based interventions for this disorder.
Paula Oliveira   +16 more
doaj   +1 more source

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