Results 41 to 50 of about 2,557,871 (296)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
SensorsEvidence is increasing for digital health programs targeting the secondary prevention of stroke. We aimed to determine the feasibility of the novel Care Assistant and support Program for people after Stroke (CAPS) or transient ischaemic attack (TIA) by ...
Liam P. Allan +9 more
doaj +1 more source
Frontiers in Surgery, 2020 Objectives: Postoperative follow-up after cochlear implantation lacks a reliable screening method to detect cochlear implant receiver device migration. This study aims to validate a clinically applicable method to assess the position and migration of the
Laura M. Markodimitraki +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Oman Medical Journal, 2020 Objectives: The literature has described several positive outcomes related to diabetes management via nurse-led clinics. This is especially true where a shortage of physicians is recorded within a team-based approach. We sought to explore the perceptions
Kamila Al-Alawi, Ahmed Al-Mandhari
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Pilot Rock Notice of Adopted Amendment (2007-05-07)
, 2007 9 pp. Adopted 2007-05-07. Department of Land Conservation and Development Notice of Adopted AmendmentWe annexed 445 acres into the City of Pilot Rock.
Pilot Rock (Or.)
core +1 more source
, 2023 We describe the two ELG open calls for pilot projects, the objective of which was to demonstrate the use and the advantages of ELG in providing basic LT for applications and as a basis for more advanced LT-based modules or components useful to industry ...
Hamrlová, Jana +2 more
core +2 more sources
Columbia World Projects First Forum Report on Inequality: Unequal Opportunity [PDF]
, 2018 This report is the first in a series of inequality reports to be issued by Columbia World Projects (CWP), summarizing expert discussions held on different aspects of economic inequality, in an effort to identify concrete, implementable ideas for how ...
Columbia World Projects
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source