Results 221 to 230 of about 8,259 (312)

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

open access: yesThe FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo   +6 more
wiley   +1 more source

Long-Term Sequelae of Primary Tooth Injuries on Permanent Successors: A Case Series. [PDF]

open access: yesCureus
Goswami M   +5 more
europepmc   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

Optically Controlled Bias-Free Frequency Reconfigurable Antenna. [PDF]

open access: yesSensors (Basel)
Younus KM   +3 more
europepmc   +1 more source

Development and modeling of a solid‐state microdosimeter for proton therapy applications

open access: yes
Precision Radiation Oncology, EarlyView.
Dante Guido Mercado   +7 more
wiley   +1 more source

UC2‐ESP: A general‐purpose framework for open‐source microscopy control

open access: yesJournal of Microscopy, EarlyView.
Abstract Building the optical setup for investigating biological questions comes with challenges. A major such challenge is setting up and synchronizing the control of multiple hardware components such as stages, cameras and lasers. With UC2‐ESP, we present a low‐cost electronics system powered by the ESP32 microcontroller (∼$10), designed as an ...
Benedict Diederich   +5 more
wiley   +1 more source

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