Results 121 to 130 of about 1,796,810 (372)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

DFAST: a flexible prokaryotic genome annotation pipeline for faster genome publication

open access: yesBioinform., 2017
Summary: We developed a prokaryotic genome annotation pipeline, DFAST, that also supports genome submission to public sequence databases. DFAST was originally started as an on‐line annotation server, and to date, over 7000 jobs have been processed since ...
Yasuhiro Tanizawa   +2 more
semanticscholar   +1 more source

The SARS-CoV-2 Vaccine Pipeline: an Overview

open access: yesCurrent Tropical Medicine Reports, 2020
Purpose of Review The goal of this review is to provide a timely overview on efforts to develop a vaccine for the 2019 novel coronavirus SARS-CoV-2, the causative agent of coronavirus disease (COVID-19).
Wen-Hsiang Chen   +3 more
semanticscholar   +1 more source

Spherical shield Patent [PDF]

open access: yes, 1965
Flexible bellows joint shielding sleeve for propellant transfer ...
Noreen, S. J., Pfleger, R. O.
core   +1 more source

Frame Combination Techniques for Ultra High-Contrast Imaging

open access: yes, 2008
We summarize here an experimental frame combination pipeline we developed for ultra high-contrast imaging with systems like the upcoming VLT SPHERE instrument. The pipeline combines strategies from the Drizzle technique, the Spitzer IRACproc package, and
Beuzit, Jean-Luc   +6 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

LFG without C-structures [PDF]

open access: yes, 2010
We explore the use of two dependency parsers, Malt and MST, in a Lexical Functional Grammar parsing pipeline. We compare this to the traditional LFG parsing pipeline which uses constituency parsers.
Cahill, Aoife   +5 more
core   +1 more source

JINA-NuGrid Galactic Chemical Evolution Pipeline

open access: yes, 2016
Galactic chemical evolution is a topic that involves nuclear physics, stellar evolution, galaxy evolution, observation, and cosmology. Continuous communication and feedback between these fields is a key component in improving our understanding of how ...
Côté, Benoit   +7 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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