Results 111 to 120 of about 14,807 (258)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

A Pilot Study for the CSST Slitless Spectroscopic Quasar Survey Based on Mock Data

open access: yesThe Astrophysical Journal
The wide survey of the Chinese Space Station Telescope (CSST) will observe a large field of 17,500 deg ^2 . The GU, GV, and GI grism observations of CSST will cover the wavelength range from 2550 to 10000 Å at a resolution of R  ∼ 200 and a depth of ...
Yuxuan Pang   +6 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

open access: yesAdvanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt   +8 more
wiley   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

open access: yesAdvanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes   +4 more
wiley   +1 more source

NON-WELDED SEALED FITTINGS FOR SMALL DIAMETER PIPELINES

open access: yesHerald of Polotsk State University. Series B. Industry. Applied Sciences
An analysis of domestic and foreign designs of non-welded sealed fittings for small diameter pipelines and tubing is carried out, the grades of materials used are considered, the designs of fittings with clamping and thrust rings and fittings with a cutting ring are presented.
N. POPOK, A. BALYSH
openaire   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

open access: yesAdvanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice   +2 more
wiley   +1 more source

Modular global-fit pipeline for LISA data analysis

open access: yesPhysical Review D
We anticipate that the data acquired by the Laser Interferometer Space Antenna (LISA) will be dominated by the gravitational wave signals from several astrophysical populations. The analysis of these data is a new challenge and is the main focus of this paper.
Senwen Deng   +5 more
openaire   +2 more sources

Laser Metal Powder Deposition of Titanium Microalloyed HSLA Steel FeC0.12Si0.25Mn1.3

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates the additive manufacturing of titanium‐doped high‐strength low‐alloy (HSLA) steel via laser metal deposition. It reveals distinct process‐structure relationships for elemental powder blends compared to prealloyed feedstocks.
Olaf Stelling   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy