Results 71 to 80 of about 637,926 (286)

Software Pipelining of Nested Loops [PDF]

open access: yes, 2001
Software pipelining is a technique to improve the performance of a loop by overlapping the execution of several iterations. The execution of a software-pipelined loop goes through three phases: prolog, kernel, and epilog. Software pipelining works best if most of the time is spent in the kernel phase rather than in the prolog or epilog phases. This can
Kalyan Muthukumar, Gautam Doshi
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

A metamorphic robot suitable for rigid miniature pipelines

open access: yesJixie chuandong
ObjectiveTo address the limited adaptability of traditional pipeline robots in complex working environments, a design proposal for a shape memory alloy (SMA) driven peristaltic metamorphic robot suitable for rigid miniature pipelines was presented ...
JIA Xiaoli   +4 more
doaj   +2 more sources

Using fast and accurate simulation to explore hardware/software trade-offs in the multi-core era [PDF]

open access: yes, 2011
Writing well-performing parallel programs is challenging in the multi-core processor era. In addition to achieving good per-thread performance, which in itself is a balancing act between instruction-level parallelism, pipeline effects and good memory ...
Carlson, Trevor   +5 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Animação Livre: uma proposta para uma pipeline e fluxo de trabalho baseados em Software Livre [PDF]

open access: yes, 2011
OpenLab ESEV is a project of the Polytechnic Institute of Viseu’s School of Education that aims to promote, foster and support the use of Free/Libre and Open Source Software (F/LOSS), Free file formats and more flexible copyright licenses for creative ...
Figueiredo, Maria Pacheco   +1 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Solution of a Gas Pipeline Buried in Ground by Stochastic Approach

open access: yesJournal of Mechanical Engineering, 2020
The paper deals with stress and reliability calculation of a gas pipeline straight section buried in a ground (elastic foundation) loaded by heating and internal overpressure.
Silvia Mihelová   +2 more
doaj   +1 more source

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