Results 191 to 200 of about 112,527 (314)

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

open access: yesAdvanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García   +11 more
wiley   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

open access: yesAdvanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li   +9 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Influence of Microstructure on DWTT Performance of Thin-wall X65M Pipeline Steel

open access: yesTeshugang
The paper addresses the issue of fluctuating low-temperature drop-weight tear test (DWTT) performance in 6-8 mm thin-wall pipeline steel, the influencing factors of the control process of low-temperature DWTT of X65 thin-wall pipeline steel have been ...
Zhang Ming
doaj  

Fatigue Life Anisotropy of API 5L X42 Pipeline Steel in Axial Force-Controlled Tests. [PDF]

open access: yesMaterials (Basel)
Beltrán-Zúñiga MA   +6 more
europepmc   +1 more source

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