Results 71 to 80 of about 111,822 (311)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Productivity and Efficiency of US Gas Transmission Companies: A European Regulatory Perspective [PDF]

open access: yes, 2008
Keywords JEL Classification On both sides of the Atlantic the regulation of gas transmission networks has undergone major changes since the early 1990’s.
Jamasb, Tooraj   +2 more
core   +4 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Numerical Analysis of Stress on Pipelaying End of Subsea Single-layer Pipeline

open access: yesShiyou jixie, 2022
Aiming at the cracking of the concrete weight coating near the tensioner and the failure of the pipeline caused by the excessive slip of the steel pipe, steel bar and concrete interface in the process of laying the subsea single-layer pipeline, the ANSYS
Ma Guorui   +3 more
doaj  

The impact of hydrogen on the ductility loss of bainitic Fe–C alloys [PDF]

open access: yes, 2016
The influence of hydrogen on the mechanical properties of generic lab-cast Fe-C bainitic alloys is studied by tensile tests on notched samples. The bainitic microstructure is induced in a 0.2% C and 0.4% C Fe-C alloy by an appropriate heat treatment. The
Depover, Tom   +2 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Effect of Heat Treatment on Mechanical Property and Electrochemical Corrosion Behavior of X65 Pipeline Steel in 3.5 wt.% NaCl

open access: yesInternational Journal of Electrochemical Science, 2015
The effect of heat treatment on the mechanical property and electrochemical corrosion behavior of X65 pipeline steel in 3.5 wt.% NaCl solution (pH=3.5) is investigated.
Hongwei Wang, Chi Yu, Shaowen Huang
doaj   +1 more source

Mechanical Anisotropy in Steels for Pipelines

open access: yesISIJ International, 2013
There has been a huge expansion in the laying of pipelines for the transmission of fossil fuels over large distances and in dire environments. One particular problem associated with the steels used to fabricate the pipes is that of the anisotropy of mechanica lp roperties, especially the toughness. This review represents an attempt to critically assess
Joo, MS, Suh, DW, Bhadeshia, HKDH
openaire   +3 more sources

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

R&D Progress on High Strength Pipeline Steel at Home and Abroad

open access: yesTeshugang, 2013
Based on published patented manufactured technologies for high strength pipeline steel including heavy plate, hot rolled coil and seamless tube at home and abroad in 2011.
陈妍, 牟昊, 齐殿威
doaj  

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