Results 231 to 240 of about 97,443 (299)

Piperazine: A Promising Scaffold with Analgesic and Anti-inflammatory Potential

Drug Research, 2020
Piperazine, a nitrogen-containing heterocyclic has acquired an inimitable position in medicinal chemistry because of its versatile structure, which has fascinated researchers to design novel piperazine based molecules having various biological actions ...
Akash Jain, Jasmine Chaudhary, Harpreet Khaira, B. Chopra, A. Dhingra   +4 more
semanticscholar   +1 more source

Recent advances in the synthesis of piperazine based ligands and metal complexes and their applications.

Dalton Transactions, 2020
The piperazine scaffold is a privileged structure frequently found in biologically active compounds. Piperazine nucleus is found in many marketed drugs in the realm of antidepressants (amoxapine), antipsychotics (bifeprunox), antihistamines (cyclizine ...
R. Kant, S. Maji
semanticscholar   +1 more source

A facile and versatile strategy for fabricating thin-film nanocomposite membranes with polydopamine-piperazine nanoparticles generated in situ

Journal of Membrane Science, 2019
We propose in this study a facile and versatile strategy for fabricating thin-film nanocomposite (TFN) membranes, wherein polydopamine-piperazine (PDP) nanoparticles were formed in situ from the oxidative polymerization reaction of dopamine and its ...
Micah Belle Marie Yap Ang, Yan-li Ji, Shu-Hsien Huang, Kueir-Rarn Lee, J. Lai   +4 more
semanticscholar   +1 more source

Novel piperazine and morpholine substituted quinolines: Selective synthesis through activation of 3,6,8-tribromoquinoline, characterization and their some metabolic enzymes inhibition potentials

, 2020
Regioselective routes are described for convenient preparation of novel piperazine/morpholine substituted quinoline derivatives at C-3, C-6 and C-8 starting with 3,6,8-tribromoquinoline (6) by nucleophilic substitution via conventional heating or ...
O. Çakmak, Salih Ökten, Dilek Alimli, C. Ersanlı, Parham Taslimi, U. M. Kocyigit   +5 more
semanticscholar   +1 more source

Intumescent flame retardant behavior of charring agents with different aggregation of piperazine/triazine groups in polypropylene

Polymer degradation and stability, 2019
To explore the structure mode of charring agent with higher flame retardant efficiency, two charring agents (PT-Cluster and PT) with different aggregation structure of piperazine/triazine groups were synthesized and characterized, and then were applied ...
Wei Tang, Lijun Qian, Yajun Chen, Y. Qiu, Bo Xu   +4 more
semanticscholar   +1 more source

Sustained-Release Dual-Drug Ternary Salt Cocrystal of Piperazine Ferulate with Pyrazinamide: Synthesis, Structure, and Hirshfeld Surface Analysis

, 2020
A novel dual-drug ternary salt cocrystal of piperazine ferulate (PRZ–FLA) with pyrazinamide (PRA), namely, PRZ–FLA–PRA, has been synthesized and characterized.
Xueke Yu, Ling-Yang Wang, Fang Liu, Yan-Tuan Li, Zhiyong Wu, Cuiwei Yan   +5 more
semanticscholar   +1 more source

Recent development of piperazine and piperidine derivatives as antipsychotic agents.

Mini-Reviews in Medical Chemistry, 2020
Schizophrenia is a chronic neuropsychiatric disorder that affects nearly 1% of the global population. There are various anti-psychotic drugs available for the treatment of schizophrenia, but they have certain side effects, therefore there is a need to ...
Akash Rathore, V. Asati, S. Kashaw, Shivangi Agarwal, Deepa Parwani, Sushanta Bhattacharya, Chaitali Mallick   +6 more
semanticscholar   +1 more source

Substituted Sulfonyl Piperazines

Journal of Pharmaceutical Sciences, 1962
Abstract In view of reports in the literature on the anticonvulsant action of various sulfonyl piperazines and of certain substituted 1-sulfonyl-4- β -aminoethylpiperazines as antishock agents, a series of mono- and disulfonyl β -aminoethylpiperazines have been prepared.
W E, LANGE, R N, LAZARUS, M E, AMUNDSON
openaire   +2 more sources

The Role of Hydrogen-Bond Between Piperazine and Fullerene Molecules in Stabilizing Polymer:Fullerene Solar Cell Performance.

ACS Applied Materials and Interfaces, 2020
Piperazine was recently reported as stabilizer for polymer:fullerene solar cells that can minimize the "burn-in" degradation of the cell. In this paper, the influence of N-substituents on the stabilization effect of piperazine in P3HT:PC61BM cells was ...
Zerui Li, Jiankai Shan, Lingpeng Yan, Huimin Gu, Yi Lin, H. Tan, Chang-Qi Ma   +6 more
semanticscholar   +1 more source

Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 1.

Journal of Agricultural and Food Chemistry, 2022
N. Meanwell, O. Loiseleur
semanticscholar   +1 more source