Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding
Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i ...
Keith E. Gordon +2 more
exaly +3 more sources
Solid lipid nanoparticles enhance piracetam’s neuroprotective action in streptozotocin-induced cognitive dysfunction [PDF]
Diabetes-induced cognitive dysfunction remains an unaddressed medical concern across the globe with limited options left with conventional drug therapy.
Abhishek Mishra +2 more
doaj +2 more sources
Pharmacokinetics and Bioequivalence Evaluation of Piracetam Tablet: A Randomized, Single-Dose, Two-Period, Crossover Study in Healthy Chinese Participants Under Fasting and Fed Conditions [PDF]
Background Piracetam, a nootropic drug, is widely used for treating cognitive impairments. However, pharmacokinetic and bioequivalence data for piracetam formulations in the Chinese population are limited.
Hegui Yan +10 more
doaj +2 more sources
Effects of Piracetam and Hyperbaric Oxygen on Histopathological and Circulating Biochemical Responses Following Sciatic Nerve Crush Injury in Rats [PDF]
Background and Objectives: Peripheral nerve injury initiates a series of degenerative, inflammatory, and reparative responses. Piracetam and hyperbaric oxygen (HBO) have been proposed as potential therapeutic interventions; however, their effects during ...
Umut Caner Canoğlu +6 more
doaj +2 more sources
Piracetam as Neuroprotective, Anticonvulsant, and Anti-Anxiety Agent: An In Vivo Study on Ptz Epileptic Rats [PDF]
Recurrent seizures characterize epilepsy, a category of neurological disorder. Epileptic seizures can result in sudden changes in brain electrical activity. Piracetam is a cyclic aminobutyric acid derivative with neuroprotective effects.
Tahereh Karimi shayan +3 more
doaj +2 more sources
Elucidating the Three‐Dimensional Structure of Piracetam through Rotational Spectroscopy [PDF]
Herein we report on the most stable structures adopted by piracetam, a nootropic drug, in isolated conditions. A chirped pulse Fourier transform microwave spectrometer (CP‐FTMW) coupled with a laser ablation source has been employed to explore the ...
S. Mato +4 more
doaj +2 more sources
Effectiveness of piracetam in cortical myoclonus
AbstractTwenty‐one patients with disabling spontaneous, reflex, or action myoclonus due to various causes, who had shown apparent clinical improvement on introduction of piracetam, entered a placebo‐controlled double‐blind crossover trial of piracetam (2.4– 16.8 g daily).
Peter Brown, John Rothwell, B L Day
exaly +3 more sources
Effectiveness and Safety of Ginkgo biloba, Vinpocetine and Piracetam as a Single Agent and Fixed Dose Combination in Patients with Subjective Tinnitus [PDF]
Introduction: Owing to the lack of any standard treatment, subjective tinnitus can be debilitating, manifesting a varied population response to tinnitus management.
Paul Mathai, Anu Chandran, Sourav Das
doaj +1 more source
Dissociative symptoms secondary to piracetam: a case report
Piracetam is a cyclic derivative of gamma-aminobutyric acid that is often used in neurology. Piracetam is an antithrombotic, neuroprotective agent which improves cognitive performance. Piracetam is indicated for vertigo in clinical practice.
Adem Aydin +4 more
doaj +1 more source
Alzheimer's disease is a cerebrovascular disorder characterized by progressive loss of the mental capabilities. The novel therapeutic agent piracetam is a cyclic derivative of γ-aminobutyric acid and one of the oldest recognized synthetic nootropics ...
Subhash Chaturvedi +3 more
doaj +1 more source

