Cocaine abuse is known to alter mitochondrial biogenesis and induce epigenetic modification linked with neuronal dysfunction. Cocaine-induced epigenetic modification of DNA methylation and the mitochondrial genome may affect mitochondrial DNA (mtDNA) and
Kalaiselvi Sivalingam, T. Samikkannu
semanticscholar +1 more source
Pharmacological management of immune and oxidative disturbances in patients with encephalopathy on the background of hypertension [PDF]
Inclusion of a comprehensive drug treatment of patients with discirculatory encephalopathy cerebrolysin combination with meksidol normalizes the concentration of C3 and C4 components of the complement system, IgG, malondialdehyde, catalase activity ...
Bistrova, N. A. +2 more
core +2 more sources
A comparative evaluation of neuroprotective activity of perindopril and valsartan in rats
Background: Angiotensin II receptor blockers and Angiotensin-converting enzyme inhibitors are widely used drugs for cardiovascular disorders, renal disease, and diabetes.
Pratiksha Vijaysinh Dhamal +1 more
doaj +1 more source
We present a novel approach to efficiently implement thermal expansion in the quasi-harmonic approximation (QHA) for both isotropic and more importantly, anisotropic expansion.
Abraham, Nathan S., Shirts, Michael R.
core +2 more sources
„Cognitive Enhancement" or non-evidence-based nootropic abuse? – Use of Piracetam in Hungary
Piracetam has been available on the market since 1971. Its primary indication is the age-related memory decline. The objective of this review is to highlight the controversies surrounding in the use of piracetam.
András Érszegi +4 more
doaj +1 more source
Effects of parenteral papaverine and piracetam administration on cochlea following acoustic trauma
Introduction: Noise exposure, the main cause of hearing loss in countries with lot of industries, may result both in temporary or permanent hearing loss.
Nurcan Yurtsever Kum +5 more
doaj +1 more source
Ginkgo biloba extract and long-term cognitive decline: a 20-year follow-up population-based study.
BackgroundNumerous studies have looked at the potential benefits of various nootropic drugs such as Ginkgo biloba extract (EGb761®; Tanakan®) and piracetam (Nootropyl®) on age-related cognitive decline often leading to inconclusive results due to small ...
Hélène Amieva +4 more
doaj +1 more source
Neuropharmacological aspects of cognitive neurorehabilitation in epilepsy. [PDF]
The role of CNS neuromodulators in cognitive neurorehabilitation can be related to two main issues: 1) the negative impact on cognition of drug categories prescribed for different neurologic symptoms, such as spasticity, extrapyramidal symptoms, or ...
Mula, M, Trimble, MR
core +4 more sources
Synthesis and Action of N-acylphenylacetamides and N-acyl-β-ketoamides on the Central Nervous System
Introduction. One of the most promising directions in the search for biologically active compounds is the molecular design of biologically active compounds containing a known pharmacoform fragment.
I. P. Kodonidi +2 more
doaj +1 more source
Neurobehavioral Impacts of Xylazine and Piracetam Interaction on NADH Oxidase in the Rat Brain
In the present study, the effects of different doses of xylazine combined with piracetam were investigated through different behavioral experiments. Xylazine is alpha 2 adrenergic agonist a veterinary sedative, and analgesic agent.
Shaker M. Kermasha +1 more
doaj +1 more source

