Results 51 to 60 of about 2,415 (174)

Acute Neurological Complications After Transplantation in Methylmalonic Acidemia: A 35‐Patient French Cohort

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Transplantation is an effective therapeutic option to improve quality of life in patients with severe methylmalonic acidemia (MMA). However, data regarding neurological complications following transplantation remain limited. A retrospective, single‐center study was conducted at Necker Hospital (France), including MMA patients who underwent ...
Adélaïde Vissac, Eugénie Sarda, Charles‐Joris Roux, Manuel Schiff, Claire‐Marine Bérat, Juliette Bouchereau, Jean‐Baptiste Arnoux, Chloé de Puyraimond, Margaux Gaschignard, Tristan Mekdade, Ugo Cucinotta, Claire Mayer, Valérie Barbier, Jean François Benoist, Mehdi Oualha, Carmen Capito, Christophe Chardot, Myriam Dao, Aude Servais, Claire Francoz, Laurène Dehoux, Florence Lacaille, Isabelle Desguerre, Nathalie Boddaert, Pascale de Lonlay, Anaïs Brassier   +25 more
wiley   +1 more source

Synergy of piracetam and aminalon in the cerebroprotective effect of olatropyl.

Medičnì Perspektivi, 2018
Optimization of pharmacotherapy of neurological and psychosomatic diseases led to the creation of com­bined medicines containing two or more components with different mechanisms of action, differently affecting the pathogenesis and clinical ...
V. I. Mamchur, S. N. Dronov
doaj   +1 more source

Experimental substantiation of the expediency of the combined use of piracetam and metformin for pharmacological correction of cognitive disorders in conditions of prolonged hyperglycemia

Medičnì Perspektivi, 2020
Chronic hyperglycemia, insulin resistance, endothelial dysfunction, and disturbance of the integrity of the blood-brain barrier are considered as strategically important links in the development of cognitive deficits in diabetic encephalopathy.
А. E. Lievykh, N. S. Bondarenko, S. N. Dronov, V. I. Mamchur, I. V. Tverdokhlib, V. I. Zhyliuk   +5 more
doaj   +1 more source

Treatment approaches in posthypoxic myoclonus: A narrative review with expert opinion

Epilepsia, Volume 67, Issue 3, Page 1049-1065, March 2026.
Abstract Acute posthypoxic myoclonus (PHM) is a neurological complication that typically emerges within 12–48 h following cardiac arrest, often in comatose patients. It can present as generalized, multifocal, or focal myoclonus and has traditionally been associated with poor prognosis.
Marina Romozzi, Federico Tosto, David García‐Azorín, Luigi Francesco Iannone, Catello Vollono, Paolo Calabresi, Juan Luis Alcala‐Zermeno, Michael R. Sperling   +7 more
wiley   +1 more source

Development and validation of spectrophotometric methods for simultaneous estimation of citicoline and piracetam in tablet dosage form

Journal of Pharmacy and Bioallied Sciences, 2013
Context: Citicoline (CN) and piracetam (PM) combination in tablet formulation is newly introduced in market. It is necessary to develop suitable quality control methods for rapid and accurate determination of these drugs.
Akhila Sivadas, Aiswarya Sathi, Kavya Sathi, Kalpana Pravin Rahate   +3 more
doaj   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

Epilepsia, Volume 67, Issue 2, Page 696-711, February 2026.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi, Haruka Ishibashi, Yukako Nakagami, Yoko Kobayashi Takahashi, Takato Akiba, Masaharu Miyauchi, Naohiro Yamamoto, Ryoichi Inoue, Satoshi Kodama, Takafumi Kubota, Naoto Kuroda   +10 more
wiley   +1 more source

Medicinal Plants and Their Bioactive Phytochemicals as Emerging Therapeutic Strategies for Alzheimer’s Disease: An Integrative Review of Preclinical and Clinical Evidence

Scientifica, Volume 2026, Issue 1, 2026.
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid deposition, tau hyperphosphorylation, mitochondrial dysfunction, oxidative stress, neuroinflammation, and blood–brain barrier disruption, collectively leading to widespread cortical and subcortical atrophy.
Nawfal Hasan Siam, Najibah Nasrin, Sharmily Saiyara, Hridoy Saha, Debashis Paul Deb, Johirul Islam, Simone Carradori   +6 more
wiley   +1 more source

Effect of Jyotiṣmatī seed oil on spatial and fear memory using scopolamine induced amnesia in mice

Ancient Science of Life, 2015
Background: Treatment of memory impairment associated with dementia such as Alzheimer′s disease is still inadequate and requires development of new drugs. Objective: The objective was to evaluate the memory enhancing effect of Celastrus paniculatus seed
Sanket B Raut, Reshma R Parekar, Kshitij S Jadhav, Padmaja A Marathe, Nirmala N Rege   +4 more
doaj   +1 more source

Comorbidity of Attention Deficit Hyperactivity Disorder (ADHD) and Chung‐Jansen Syndrome: Case Report and Review of Literature

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Chung‐Jansen Syndrome (CJS) is a rare autosomal dominant neurodevelopmental disorder caused by heterozygous mutations in the PHIP gene (6q14.1). It is characterized by developmental delay, intellectual disability, behavioral disturbances including autism spectrum disorder and attention deficit hyperactivity disorder, obesity, and distinct ...
Maedeh Khalili, Maryam Yousefi Fahadani, Reza Bidaki, Zahra Talayi   +3 more
wiley   +1 more source

Cerebroprotective prevention of memory disorders using sodium valproate

Zaporožskij Medicinskij Žurnal, 2013
Epilepsy is the disease resulting in impaired cognitive function. The paper deals with the use of nootropics against the background of an anticonvulsant effect.
A. V. Ivanov
doaj   +1 more source