Results 191 to 200 of about 9,855 (261)

Piracetam mitigates nephrotoxicity induced by cisplatin via the AMPK-mediated PI3K/Akt and MAPK/JNK/ERK signaling pathways.

International Immunopharmacology
AIMS Cisplatin (CDDP) is commonly employed as an antineoplastic agent, but its use is significantly limited by the occurrence of dose-dependent nephrotoxicity, the detailed mechanisms of which remain unclear.
Ahmed M. El-Dessouki, Amany A. Alzokaky, N. Raslan, S. Ibrahim, Lamiaa A. Salama, E. Yousef   +5 more
semanticscholar   +1 more source

Modulation of VEGF/eNOS/TGF‐β Axis by Piracetam as a New Avenue to Ameliorate Valproic Acid‐Induced Placental Toxicity and Teratogenicity in Rats

Journal of biochemical and molecular toxicology
Valproic acid (VPA) is a very effective therapy used to treat generalized epilepsy, but it must be avoided during pregnancy as it leads to a high risk of teratogenesis.
A. Elhemiely, Wessam H. Elesawy
semanticscholar   +1 more source

Cognitive effects of piracetam in adults with memory impairment: A systematic review and meta-analysis.

Clinical neurology and neurosurgery (Dutch-Flemish ed. Print)
INTRODUCTION Piracetam, a widely recognized nootropic drug, is hypothesized to enhance memory function through its influence on synaptic plasticity and neurotransmitter levels.
F. Gouhie, K. Barbosa, A. Cruz, M. Wellichan, Tainá Montini Zampolli   +4 more
semanticscholar   +1 more source

Neuroprotective effects of novel nanosystems simultaneously loaded with vinpocetine and piracetam after intranasal administration

Life Science, 2019
Aims: The study aim was to test the efficacy of a novel created hybrid nanosystem compared to other nanosystems in treatment of scopolamine induced memory impairment.
M. Nasr, Sara A. Wahdan
semanticscholar   +1 more source

Spectrofluorimetric approach for determination of citicoline in the presence of co-formulated piracetam through fluorescence quenching of eosin Y.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2020
A simple, sensitive, and precise spectrofluorimetric method has been developed and validated for quantitation of citicoline in its pharmaceutical formulations.
Mahmoud A Omar, Amal B. Ahmed, N. Abdelwahab, M. M. Abdelrahman, S. Derayea   +4 more
semanticscholar   +1 more source

Antimyoclonic Action of Piracetam

Clinical Neuropharmacology, 1986
Five patients with myoclonus were treated with oral piracetam (8-9 g/day). All patients had action-sensitive and/or stimulus-sensitive myoclonus and enhanced amplitude of somatosensory evoked potentials. Piracetam produced a marked reduction of the myoclonus in the five subjects without side effects.
J A, Obeso, J, Artieda, M R, Luquin, J, Vaamonde, J M, Martínez Lage   +4 more
openaire   +2 more sources

Piracetam in Elderly Motorists

Pharmacopsychiatry, 1991
101 elderly motorists with reduced reaction capacity were examined under real traffic conditions with regard to their driving ability. They were given a daily dose of 4.8 g piracetam or placebo over a six-week period in a randomised double-blind study.
U, Schmidt, D, Brendemühl, K, Engels, N, Schenk, E, Ludemann   +4 more
openaire   +2 more sources

Nootropic drugs: Methylphenidate, modafinil and piracetam - Population use trends, occurrence in the environment, ecotoxicity and removal methods - A review.

Chemosphere, 2019
Pharmaceuticals which originally were designed to treat people with neurological and psychiatric conditions, e.g. Alzheimer's disease or attention deficit hyperactivity disorder (ADHD), are nowadays often misused by students as a 'brain doping ...
Wiktoria Wilms, Marta Woźniak-Karczewska, P. Corvini, Ł. Chrzanowski   +3 more
semanticscholar   +1 more source

Piracetam and Piracetam-Like Drugs

Drugs, 2010
There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since the last meta-analysis of the clinical efficacy of piracetam, more information has accumulated. The primary objective of this systematic survey is to evaluate the clinical outcomes as well as the scientific literature relating to the pharmacology ...
Andrei G, Malykh, M Reza, Sadaie
openaire   +2 more sources

Comparison of Ischemic Preconditioning and Systemic Piracetam for Prevention of Ischemia-Reperfusion Injury in Musculocutaneous Flaps

Journal of reconstructive microsurgery, 2020
Background Ischemia-reperfusion injury plays an important role in flap failure. Ischemic preconditioning technique is the only proven method for preventing ischemia-reperfusion injury, but it is not used widely in daily practice because of difficulties ...
Anıl Demiröz, H. Derebaşınlıoğlu, Alp Ercan, H. Arslan, Övgü Aydin, H. Ekmekçi, Özlem Balcı Ekmekçi, Y. Aydin   +7 more
semanticscholar   +1 more source