Results 91 to 100 of about 1,456 (263)

Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective

open access: yesAdvanced Science, EarlyView.
This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin   +4 more
wiley   +1 more source

La figlia del pirata. Idee per un commento a Senenca, Controversiae I,6

open access: yesAnnali Online dell'Università di Ferrara. Sezione Lettere, 2010
The declamation I 6 of the Elder Seneca deals with such a common topic as pirates capturing young men who uselessly ask their fathers for ransom. In this case, the intervention of the daughter of the pirate chief leads to the release of the captive, who ...
Mario Lentano
doaj   +1 more source

PROSECUTING SOMALIA PIRATES AS TERRORISTS [PDF]

open access: yesJournal of Defense Resources Management, 2011
This article starts from the assumption that piracy resembles terrorism in many aspects and attempts to support it through both a theoretical investigation and practical examples.
ODHIAMBO E.O.S., ONKWARE K., KASSILLY J., NTABO O. M.
doaj  

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu   +17 more
wiley   +1 more source

Maritime Piracy: without “internationalization” of the jurisdictional function

open access: yesACDI: Anuario Colombiano de Derecho Internacional, 2014
If the development of piracy off Somalia’s coasts seems now under control, pirates have moved and now concentrate their attacks in West Africa waters.
Jean-Marc Thouvenin
doaj  

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

Large Language Model‐Based Chatbots in Higher Education

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci   +4 more
wiley   +1 more source

Pirate

open access: yes, 2002
Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
openaire   +3 more sources

Piracy & Social Change| Piracy Versus Privacy: An Analysis of Values Encoded in the PirateBrowser

open access: yesInternational Journal of Communication, 2015
The PirateBrowser is a Web browser that uses Tor privacy-enhancing technology to circumvent nationally implemented Internet filters blocking access to The Pirate Bay.
Balázs Bodó
doaj  

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang   +5 more
wiley   +1 more source

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