ABSTRACT Background Obesity and low testosterone levels are closely interconnected, with the FTO gene being the most robust genetic determinant of body mass index (BMI). However, whether this primary genetic driver of obesity directly influences the hypothalamic‐pituitary‐testicular (HPT) axis remains unclear.
Takahiro Tsutsumi +8 more
wiley +1 more source
Central Diabetes Insipidus Following Steroid Replacement for Hypoadrenalism in Pembrolizumab-Induced Hypophysitis. [PDF]
Alasmar A, San SS, Ta T, Mani SE.
europepmc +1 more source
Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...
Fleur Veldman +7 more
wiley +1 more source
Central Adrenal Insufficiency Unmasked After Pneumonia-Associated Asthma Exacerbation Leading to the Diagnosis of Rathke's Cleft Cyst in an Elderly Woman: A Case Report. [PDF]
Yamamoto N, Ohta R, Yamasaki A, Sano C.
europepmc +1 more source
Five Advances in the Last 50 Years That Have Impacted Endocrine Surgery
World Journal of Surgery, EarlyView.
Matilda Anneback +5 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Spectrum and prognosis of CAR-T-related endocrine toxicity: glucose/calcium dysregulation, pituitary axis disorders, and overlap with CRS. [PDF]
Liang J +7 more
europepmc +1 more source
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić +25 more
wiley +1 more source
Sex-dependent effects of environmental enrichment on mood-related behaviors, central and peripheral BDNF, and adrenal catecholamine enzymes in mice. [PDF]
Herselman MF +4 more
europepmc +1 more source
A comprehensive review of cancer‐induced cardiac wasting
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena +5 more
wiley +1 more source

