Results 11 to 20 of about 2,508 (105)

Inferior petrosal sinus sampling in differential diagnosis of ACTH-dependent hypercortisolism

open access: yesЭндокринная хирургия, 2018
Survival rate of patients with endogenous hypercortisolism, as well as complications reversibility and treatment effectiveness depends on on-time and precise diagnosis. In case of apparent clinical picture with all laboratory tests confirmation, the most
Ivan I. Sitkin   +4 more
doaj   +1 more source

Recent Understanding and Future Directions of Recurrent Corticotroph Tumors

open access: yesFrontiers in Endocrinology, 2021
Corticotroph tumors (CTs) are pituitary neoplasms arising from the Tpit lineage, which may or not express adrenocorticotrophic hormone (ACTH). Functioning CTs cause Cushing’s disease (CD), which has high morbidity and mortality due to hypercortisolemia. “
José Miguel Hinojosa-Amaya   +2 more
doaj   +1 more source

Recent Progress in the Medical Therapy of Pituitary Tumors [PDF]

open access: yesEndocrinology and Metabolism, 2017
Management of pituitary tumors is multidisciplinary, with medical therapy playing an increasingly important role. With the exception of prolactin-secreting tumors, surgery is still considered the first-line treatment for the majority of pituitary ...
Fabienne Langlois   +2 more
doaj   +1 more source

Diagnostic Power of Bilateral Inferior Petrosal Sinus Sampling with Desmopressin in Paediatric Cushing's Disease

open access: yesJCRPE, 2022
INTRODUCTION: The aim of this study was to evaluate the diagnostic accuracy of bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin for pediatric Cushing's disease (CD).
Manuel André Virú-loza   +1 more
doaj   +1 more source

transsphenoidal surgery for secreting pituitary microadenomas: results with intraoperative application of absolute alcohol [PDF]

open access: yes, 2014
Background: Pituitary adenomas represent a quite frequent neurosurgical disease. Secreting pituitary adenomas are represented by PRL, GH, ACTH and TSH tumours; the rate of postoperative hormonal recurrence is not ineligible.
Fraioli, B   +4 more
core   +1 more source

Influence of mirtazapine on salivary cortisol in depressed patients [PDF]

open access: yes, 2003
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C.   +3 more
core   +1 more source

Comparative Analysis of Clinical, Hormonal and Morphological Studies in Patients with Neuroendocrine ACTH-Producing Tumours

open access: yesInternational Journal of Endocrinology, 2013
This paper highlights the problem of neuroendocrine tumours (NETs) with clinical symptoms of hypercorticism caused by hypersecretion of adrenocorticotropic hormone (ACTH) by tumour cells.
G. S. Kolesnikova   +6 more
doaj   +1 more source

Somatostatin and dopamine receptors as targets for medical treatment of Cushing's Syndrome [PDF]

open access: yes, 2008
Somatostatin (SS) and dopamine (DA) receptors are widely expressed in neuroendocrine tumours that cause Cushing's Syndrome (CS). Increasing knowledge of specific subtype expression within these tumours and the ability to target these receptor subtypes ...
A Colao   +115 more
core   +4 more sources

TRH-induced secretion of adrenocorticotropin and cortisol in dogs with pituitary-dependent hypercortisolism

open access: yesVeterinary Quarterly, 2018
Background: In dogs, spontaneous Cushing’s syndrome is most often pituitary-dependent and caused by hypersecretion of adrenocorticotropic hormone (ACTH), resulting in increased adrenocortical glucocorticoid secretion similar to horses.
Tera Pijnacker   +5 more
doaj   +1 more source

Evaluation of diagnostic potential of the collagen osteogenesis marker (P1NP) compared with osteocalcin in Cushing’s disease

open access: yesОстеопороз и остеопатии, 2019
Background: Secondary osteoporosis is a significant problem, especially in patients with endocrine pathology, which is not accompanied constantly by distinct clinical symptoms.
Timur T. Tsoriev   +3 more
doaj   +1 more source

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