Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
, 1989 We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain +19 more
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Inferior petrosal sinus sampling in differential diagnosis of ACTH-dependent hypercortisolism
Эндокринная хирургия, 2018 Survival rate of patients with endogenous hypercortisolism, as well as complications reversibility and treatment effectiveness depends on on-time and precise diagnosis. In case of apparent clinical picture with all laboratory tests confirmation, the most
Ivan I. Sitkin +4 more
doaj +1 more source
Recent Understanding and Future Directions of Recurrent Corticotroph Tumors
Frontiers in Endocrinology, 2021 Corticotroph tumors (CTs) are pituitary neoplasms arising from the Tpit lineage, which may or not express adrenocorticotrophic hormone (ACTH). Functioning CTs cause Cushing’s disease (CD), which has high morbidity and mortality due to hypercortisolemia. “
José Miguel Hinojosa-Amaya +2 more
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Recent Progress in the Medical Therapy of Pituitary Tumors [PDF]
Endocrinology and Metabolism, 2017 Management of pituitary tumors is multidisciplinary, with medical therapy playing an increasingly important role. With the exception of prolactin-secreting tumors, surgery is still considered the first-line treatment for the majority of pituitary ...
Fabienne Langlois +2 more
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JCRPE, 2022 INTRODUCTION: The aim of this study was to evaluate the diagnostic accuracy of bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin for pediatric Cushing's disease (CD).
Manuel André Virú-loza +1 more
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Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]
, 2010 We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato +9 more
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International Journal of Endocrinology, 2013 This paper highlights the problem of neuroendocrine tumours (NETs) with clinical symptoms of hypercorticism caused by hypersecretion of adrenocorticotropic hormone (ACTH) by tumour cells.
G. S. Kolesnikova +6 more
doaj +1 more source
Prolactin-adjusted inferior petrosal sinus sampling: Pituitary and ectopic adrenocorticotropic hormone-dependent Cushing syndrome. [PDF]
J NeuroendocrinolAbstract Inferior petrosal sinus sampling (IPSS) is a diagnostic procedure used to differentiate between ectopic adrenocorticotropic hormone (ACTH)‐dependent Cushing syndrome (EAS) and pituitary ACTH‐dependent Cushing syndrome (CD). This study investigated the diagnostic value of IPSS, focusing on the use of prolactin adjustments and different ...
Sprenkeler VE +6 more
europepmc +2 more sources
transsphenoidal surgery for secreting pituitary microadenomas: results with intraoperative application of absolute alcohol [PDF]
, 2014 Background: Pituitary adenomas represent a quite frequent neurosurgical disease. Secreting pituitary adenomas are represented by PRL, GH, ACTH and TSH tumours; the rate of postoperative hormonal recurrence is not ineligible.
Fraioli, B +4 more
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Veterinary Quarterly, 2018 Background: In dogs, spontaneous Cushing’s syndrome is most often pituitary-dependent and caused by hypersecretion of adrenocorticotropic hormone (ACTH), resulting in increased adrenocortical glucocorticoid secretion similar to horses.
Tera Pijnacker +5 more
doaj +1 more source