Results 71 to 80 of about 5,640 (173)
The Locus Coeruleus: Anatomy, Physiology, and Stress‐Related Neuropsychiatric Disorders
European Journal of Neuroscience, Volume 61, Issue 7, April 2025.Repeated and chronic exposure to stressors may activate the locus coeruleus–norepinephrine (LC‐NE) system. Depression and post‐traumatic stress disorders precipitated by a stressful event are associated with the hypersecretion of the corticotropin‐releasing factor (CRF) leading to elevated CRF levels in the brain (green arrows pointed up).
Beverly A. S. Reyes
wiley +1 more source
Cortisol Secreting Adrenal Adenoma in a 5 Year Old Child [PDF]
, 2011 Adrenal adenoma is a rare endocrinal tumor in children. It can present with features of Cushing's syndrome. We present a case report of five years old female child who came with morbid obesity and hypertension.
Narang, Gursharan Singh +1 more
core
Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]
, 2007 We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark +7 more
core +1 more source
EGFR and JAK2 were significant master gene biomarkers in invasive and noninvasive pituitary adenoma
Precision Medical Sciences, Volume 14, Issue 1, Page 4-14, March 2025.(A) Visualization of the interactions between upregulated and downregulated genes in invasive and non‐invasive pituitary adenomas, highlighting the central role of EGFR and JAK2 as master gene biomarkers. (B) Expression density plots show the distribution of gene expression values after normalization, and volcano plots illustrate significant DEGs ...
Afsaneh Ghasemi +6 more
wiley +1 more source
Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]
, 2000 Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J., +6 more
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Journal of Neuroendocrinology, Volume 37, Issue 3, March 2025.The thera(g)nostic approach with somatostatin analog‐based agents extends beyond gastroenteropancreatic neuroendocrine tumors. Understanding tumor biological mechanisms is essential for optimizing treatment strategies. Abstract First isolated by Brazeau et al. in 1972, somatostatin (SST) is a neuropeptide known for regulating various signaling pathways
Giulia Santo +3 more
wiley +1 more source
Grading and staging for pituitary neuroendocrine tumors
Brain Pathology, Volume 35, Issue 1, January 2025.Abstract Pituitary adenoma/pituitary neuroendocrine tumors (PitNETs) are the second most common primary intracranial tumor and the most frequent neuroendocrine tumors/neoplasms of the human body. Thus, they are one of the most frequent diagnoses in neuropathologist's practise.
Chiara Villa +6 more
wiley +1 more source
Pituitary adenomas, some diagnostic and therapeutical aspects [PDF]
, 1994 The treatment of almost all types of pituitary adenomas has changed considerably in recent years. New types of drugs as well as improved application forms of older drug therapies are now becoming more and more available for everyday treatment of patients
Herder, W.W. (Wouter) de +2 more
core +1 more source
Role of somatostatin receptors in normal and tumoral pituitary corticotropic cells [PDF]
, 2010 Normal and tumoral pituitary corticotropic cells express sst2and sst5, of which sst5is the predominantly expressed receptor subtype. Somatostatin (SS) inhibits pituitary adrenocorticotropin hormone (ACTH) secretion in vitro, but the sensitivity to SS is ...
Feelders, R.A. (Richard) +2 more
core +4 more sources
Expression of p53 protein in pituitary adenomas
Brazilian Journal of Medical and Biological Research, 2002 Inactivating mutations of TP53, a tumor suppressor gene, are associated with abnormal cell proliferation. Although p53 expression is common in many human malignancies, p53 protein has seldom been evaluated in pituitary tumors.
Oliveira M.C. +5 more
doaj