Results 91 to 100 of about 362,132 (303)
Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
arXiv, 2021 The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]
, 1933 G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P. +3 more
core
Pituitary adenoma management and outcomes according to hospital case volume and facility type
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.Abstract Objectives This study evaluates the influence of facility volume and type on the treatment and outcomes of pituitary adenoma (PA). Methods The 2004–2016 National Cancer Database was queried for patients with PA receiving definitive treatment. Tumor size represented the largest diameter of the primary tumor.
Khodayar Goshtasbi +8 more
wiley +1 more source
Pituitary calcification masquerading as pituitary apoplexy
Indian Journal of Endocrinology and Metabolism, 2013 Pituitary calcification occurs commonly in lactotroph or somatotroph adenoma but rare in chomophobe or gonadotroph adenoma. On imaging, it can mimic hemorrhage, hence may masquerade pituitary apoplexy if patient present with neurological manifestations ...
M K Garg +3 more
doaj +1 more source
Endoscopic versus microscopic transsphenoidal pituitary adenoma surgery: a meta-analysis
World Journal of Surgical Oncology, 2014 BackgroundEndoscopic transsphenoidal surgery has gradually come to be regarded as a preferred option in the treatment of pituitary adenomas because of its advantages of improved visualization and its minimal invasiveness.
Yang Gao +9 more
semanticscholar +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, EarlyView.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Endocrine reviews, 2013 Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their management involves neurosurgery, biological ...
A. Beckers +3 more
semanticscholar +1 more source
Andrology, EarlyView.Abstract Introduction Testosterone therapy has become a cornerstone treatment for men with hypogonadism, offering significant benefits such as improved sexual function, mood, muscle mass, and bone density. However, concerns about its cardiovascular safety have historically tempered its use.
Michael Zitzmann +15 more
wiley +1 more source
Паёми Сино, 2020 Multiple intracranial tumors with different histological types diagnosed in the same patient are rare. The combination of meningiomas and pituitary adenomas in most cases concerns patients who received radiation therapy for pituitary adenomas.
A.S. NECHAEVA +3 more
doaj +1 more source
Magmas overexpression inhibits staurosporine induced apoptosis in rat pituitary adenoma cell lines. [PDF]
PLoS ONE, 2013 Magmas is a nuclear gene that encodes for the mitochondrial import inner membrane translocase subunit Tim16. Magmas is overexpressed in the majority of human pituitary adenomas and in a mouse ACTH-secreting pituitary adenoma cell line.
Federico Tagliati +6 more
doaj +1 more source