Results 121 to 130 of about 364,574 (324)

Cyclin-dependent kinase inhibitor 1B (CDKN1B) gene variants in AIP mutation-negative familial isolated pituitary adenoma kindreds.

Endocrine-Related Cancer, 2012
Familial isolated pituitary adenoma (FIPA) occurs in families and is unrelated to multiple endocrine neoplasia type 1 and Carney complex. Mutations in AIP account only for 15-25% of FIPA families.
M. Tichomirowa, Misu Lee, A. Barlier, A. Daly, I. Marinoni, M. Jaffrain-Rea, L. Naves, P. Rodien, V. Rohmer, F. Faucz, P. Caron, B. Estour, P. Lecomte, F. Borson‐Chazot, A. Penfornis, M. Yaneva, M. Guitelman, Emily Castermans, C. Verhaege, J. Wemeau, A. Tabarin, C. Fajardo Montañana, B. Delemer, V. Kerlan, J. Sadoul, Christine Cortet Rudelli, F. Archambeaud, S. Zacharieva, M. Theodoropoulou, T. Brue, A. Enjalbert, V. Bours, N. Pellegata, A. Beckers   +33 more
semanticscholar   +1 more source

Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost‐Effectiveness Perspective

Clinical Endocrinology, Volume 103, Issue 2, Page 216-224, August 2025.
ABSTRACT Objective Patients require additional treatment when pituitary surgery for Cushing's disease is unsuccessful. Exciting innovations in pituitary surgery bring hope for achieving better outcomes. Quantifying the potential value of these innovations using early health economic modelling can provide guidance throughout their development.
Femke J. C. Jacobs, Tim M. Govers, Jurgen J. Fütterer, Annenienke van de Ven, Maroeska M. Rovers   +4 more
wiley   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, Volume 12, Issue 25, July 3, 2025.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

siRNA-mediated silencing of bFGF gene inhibits the proliferation, migration, and invasion of human pituitary adenoma cells

Tumor Biology, 2017
Human pituitary adenoma is one of the most common intracranial tumors with an incidence as high as 16.7%. Recent evidence has hinted a relationship between growth factors of pituitary or hypothalamic origin and proliferation of human pituitary adenoma ...
Kai Zhou, Yan-Dong Fan, Serick Duysenbi, Peng-Fei Wu, Zhao-Hai Feng, Zheng Qian, Ting-Rong Zhang   +6 more
doaj   +1 more source

EXTRASELLAR EXTENSION OF PITUITARY ADENOMAS [PDF]

, 1966
Erich G. Krueger, Sol M. Unger
openalex   +1 more source

Diagnostic pathology of equine intracranial neoplasms

Equine Veterinary Education, EarlyView.
H. G. Miller, A. Suarez‐Bonnet
wiley   +1 more source

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 2070-2079, July 2025.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo, Ajay Madan, Christine T. Ferrara‐Cook, Deepak Dalvie, Lance Goulet, R. Scott Struthers, Alan S. Krasner   +6 more
wiley   +1 more source

Acromegaly with no pituitary adenoma and no evidence of ectopic source

Indian Journal of Endocrinology and Metabolism, 2011
More than 99% of patients with acromegaly harbor a growth hormone (GH) secreting pituitary adenoma. As the time from onset of signs/symptoms to diagnosis of acromegaly is long (symptom onset to diagnosis is often 4-10 years), pituitary adenomas that ...
Deepak Khandelwal, Rajesh Khadgawat, Amar Mukund, Ashish Suri   +3 more
doaj   +1 more source

Whole-Exome Sequencing Study of Thyrotropin-Secreting Pituitary Adenomas [PDF]

, 2018
学位記番号 ...
Santosh, Sapkota, Santosh, Sapkota, サントス, サプコタ   +2 more
core  

Computed tomographic features of pituitary apoplexy in a cat

Journal of Small Animal Practice, EarlyView.
W. Swan, M. Taylor, I. Orgonikova, J. M. De Frias   +3 more
wiley   +1 more source