Results 61 to 70 of about 158,592 (235)

Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal alpha-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition [PDF]

open access: yes, 2012
PMCID: PMC3534021This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Chrisostomos Prodromou   +33 more
core   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

open access: yesPediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu   +5 more
wiley   +1 more source

Effects of proton therapy on the tumor immune system and clinical implications: A review

open access: yesPrecision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu   +5 more
wiley   +1 more source

EGFL7 participates in regulating biological behavior of growth hormone–secreting pituitary adenomas via Notch2/DLL3 signaling pathway

open access: yesTumor Biology, 2017
Growth hormone–secreting pituitary adenoma accounts for about 20% of the third most common intracranial neoplasm—pituitary adenomas—which makes up 15% of all intracranial tumors.
Jianpeng Wang   +6 more
doaj   +1 more source

Calcification in Pituitary Adenomas

open access: yesNeurologia medico-chirurgica, 1983
Though radiographically-proven calcifications in pituitary adenomas are rare, a higher incidence of microscopically-proven calcified adenomas has been recently reported. Therefore, the incidence of radiological and microscopical calcifications in various types of pituitary adenomas in a consecutive series of 169 cases (71 acromegalies, 54 prolactinomas,
KATO, Tetsuo   +3 more
openaire   +3 more sources

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello   +4 more
wiley   +1 more source

A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis

open access: yesIndian Journal of Pathology and Microbiology, 2023
Dual pathology in the pituitary gland is a unique phenomenon. Coexistence of a pituitary adenoma with primary hypophysitis has been reported rarely with very few cases in the literature.
Sanjiban Patra, Priti Trivedi
doaj   +1 more source

A Recurrent Tympanicum Paraganglioma With a SDHD Pathogenic Variant: Fourth Reported Case

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The aim of this study is to describe a clinical case of a SDHD germline mutation associated tympanic paraganglioma (TPGL). Patients A female patient seen in the otology clinic at a tertiary care center with a diagnosis of tympanic paraganglioma and significant family history of head and neck paragangliomas.
Alex Z. Graboyes   +3 more
wiley   +1 more source

AI‐Based Automated Instrument Tracking During Endoscopic Skull Base Surgery: A Pilot Feasibility Study

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Endoscopic endonasal approaches (EEA) to skull base tumors are a technically challenging procedure for both surgeons and trainees. Artificial intelligence and computer vision (CV) may offer an objective analysis that provides surgical assessment on technique and enhanced educational feedback for surgeons of all levels.
David R. Grimm   +14 more
wiley   +1 more source

Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data

open access: yesInternational Journal of Endocrinology, 2015
Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas.
Peng Zhao   +7 more
doaj   +1 more source

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