Results 1 to 10 of about 6,245 (175)

Pituitary Adenylate Cyclase-Activating Polypeptide in Learning and Memory [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2021
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a highly conserved neuropeptide that regulates neuronal physiology and transcription through Gs/Gq-coupled receptors. Its actions within hypothalamic, limbic, and mnemonic systems underlie its
Marieke R. Gilmartin, Nicole C. Ferrara
doaj   +5 more sources

Calcitonin Gene-Related Peptide (CGRP) and Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in Migraine Pathogenesis [PDF]

open access: yesPharmaceuticals, 2022
Migraine is a prevalent and debilitating neurologic disorder. Advancements in understanding the underlying pathophysiological mechanisms are spearheading the effort to introduce disease-specific treatment options.
Casper Emil Christensen   +2 more
doaj   +2 more sources

Effects of Pituitary Adenylate Cyclase Activating Polypeptide on Cell Death. [PDF]

open access: yesInt J Mol Sci, 2022
Pituitary adenylate cyclase activating polypeptide (PACAP) was first isolated as a hypothalamic peptide based on its efficacy to increase adenylate cyclase (AC) activity. It has a widespread distribution throughout the body including the nervous system and peripheral organs, where PACAP exerts protective effects both in vivo and in vitro through its ...
Horvath G, Reglodi D, Fabian E, Opper B.
europepmc   +3 more sources

Relationship between Plasma Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Level and Proteome Profile of Cows [PDF]

open access: yesAnimals, 2022
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic and multifunctional neuropeptide; it takes part in the regulation of various physiological processes, such as feeding, reproduction, catecholamine synthesis, thermoregulation ...
Levente Czegledi   +2 more
doaj   +2 more sources

The pituitary adenylate cyclase-activating polypeptide system as a sex-specific modulator of hippocampal response to threat stimuli [PDF]

open access: yesNeurobiology of Stress, 2022
Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) receptor gene polymorphism has been postulated as a potential sex-specific diagnostic biomarker of trauma-related disorders.
Daniel Porta-Casteràs   +4 more
doaj   +2 more sources

Corrigendum: Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP) [PDF]

open access: yesFrontiers in Neuroscience, 2020
João C. R. Cardoso   +2 more
doaj   +2 more sources

Pituitary Adenylate Cyclase Activating Polypeptide [PDF]

open access: yesThe American Journal of Pathology, 2010
Sweat secretion is the major function of eccrine sweat glands; when this process is disturbed (paridrosis), serious skin problems can arise. To elucidate the causes of paridrosis, an improved understanding of the regulation, mechanisms and factors underlying sweat production is required.
Stephan Seeliger   +12 more
openaire   +4 more sources

Pituitary Adenylate Cyclase Activating Peptide and Post-traumatic Stress Disorder: From Bench to Bedside

open access: yesFrontiers in Psychiatry, 2022
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide with isoforms consisting of either 27 or 38 amino acids. PACAP is encoded by the adenylate cyclase activating peptide gene, ADCYAP1, in humans and the highly conserved ...
Manessa Riser, Seth Davin Norrholm
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide: A Potent Therapeutic Agent in Oxidative Stress

open access: yesAntioxidants, 2021
Stroke is a life-threatening condition that is characterized by secondary cell death processes that occur after the initial disruption of blood flow to the brain.
Nadia Sadanandan   +10 more
doaj   +1 more source

A Broad Overview on Pituitary Adenylate Cyclase-Activating Polypeptide Role in the Eye: Focus on Its Repairing Effect in Cornea

open access: yesApplied Sciences, 2022
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is a neuropeptide with widespread distribution throughout the central and peripheral nervous system as well as in many other peripheral organs.
Grazia Maugeri   +2 more
doaj   +1 more source

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