Results 141 to 150 of about 6,245 (175)
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Copper(II) complexation by pituitary adenylate cyclase activating polypeptide fragments
Journal of Inorganic Biochemistry, 1999Results are reported from potentiometric and spectroscopic (UV-Vis, CD, and ESR) studies of the protonation constants and Cu2+ complex stability constants of pituitary adenylate cyclase activating polypeptide fragments (HSDGI-NH2, TDSYS-NH2, RKQMAVKKYLAAVL-NH2).
T, Kowalik-Jankowska +2 more
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Pituitary adenylate cyclase activating polypeptide (PACAP) in human ovarian cancers
Cancer Letters, 1998Synthesis of regulatory peptides has been described in a number of ovarian tumours. The recently isolated neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) is expressed transiently in steroidogenic cells of normal rat ovary.
L, Odum, J, Fahrenkrug
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Neuroprotective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide
International Journal of Advance Innovations, Thoughts & Ideas, 2014Pituitary adenylate cyclase-activating polypeptide (PACAP) is a member of the secretin/glucagon/vasoactive intestinal peptide (VIP) super family. PACAP was first isolated from an ovine hypothalamus and named because it stimulated cAMP production in the rat pituitary cell culture.
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Pituitary adenylate cyclase-activating polypeptide induces hyperthermia in the rat
Neuropharmacology, 2000The effects of centrally administered pituitary adenylate cyclase-activating polypeptide (PACAP-38) on body temperature were investigated in rats. Intracerebroventricular (i.c.v.) administration of PACAP-38 in doses of 500 and 1000 ng induced a dose-related elevation in colon temperature 2, 3, 4, 5 and 6 h after injection. The i.c.v.
I, Pataki +4 more
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Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons
Regulatory Peptides, 1995Pituitary adenylate cyclase activating polypeptide (PACAP) is a novel vasoactive intestinal peptide (VIP)-like peptide, which is present in neuronal elements of several peripheral organs, and thus a putative neurotransmitter/modulator. In the present study, the expression of PACAP in two parasympathetic ganglia (otic, sphenopalatine) and one mixed ...
H, Mulder +6 more
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Pituitary Adenylate Cyclase-Activating Polypeptide Relaxes Rat Gastrointestinal Smooth Muscle
Scandinavian Journal of Gastroenterology, 1992Pituitary adenylate cyclase-activating polypeptide (PACAP) is a new member of the secretin/glucagon peptides family, being most homologous to vasoactive intestinal peptide (VIP). The present study was designed to investigate a possible effect of PACAP on the rat gastrointestinal smooth muscle in vitro. We demonstrated that 1) PACAP reduced basal smooth-
Z, Mungan +4 more
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Pituitary adenylate cyclase-activating polypeptide stimulates secretion in T84 cells
Gastroenterology, 1992Pituitary adenylate-cyclase-activating peptide (PA-CAP) and PACAP-27 are novel hypothalamic peptides that can stimulate adenylate cyclase in cultured anterior pituitary cells. Because these peptides are present in the gut and are homologous with vasoactive intestinal peptide (VIP), itself known to stimulate intestinal ion transport, we examined the ...
T D, Nguyen, G G, Heintz, J A, Cohn
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Aggressive pituitary tumours and pituitary carcinomas
Nature Reviews Endocrinology, 2021Pr Gerald Raverot +2 more
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