Results 41 to 50 of about 4,412 (188)

Shedding light on canine pituitary dwarfism [PDF]

, 2015
Pituitary dwarfism, associated with growth hormone deficiency, is an autosomal, recessively inherited disorder in shepherd dogs. Due to the serious nature of pituitary dwarfism and lack of efficient treatment, it is preferable to prevent dwarfs from ...
Voorbij, A.M.W.Y.
core  

Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency [PDF]

Annals of Pediatric Endocrinology & Metabolism
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy.
Chiara Rodaro, Gianluca Tamaro, Elena Faleschini, Gianluca Tornese   +3 more
doaj   +1 more source

Multiancestry and Multitrait GWAS Meta‐Analysis on Schizophrenia With a Sample of 322,321 Unveils Genetic Links to Chronic Lung Diseases

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
This study integrated GWAS data for schizophrenia from European (PGC, FinnGen, iPSYCH) and East Asian cohorts with GWAS of chronic pulmonary diseases (COPD, asthma, ILD, pneumonia) and lung function traits, alongside transcriptomic and proteomic datasets (GEO, GTEx, CommonMind, pQTL).
Abudusalamu Ayoufu, Ayinigeer Abulimiti, Wusimanjiang Aierken, ZhouBin Wei, XueCheng Wang, HaiFeng Wang, Liang Zhao   +6 more
wiley   +1 more source

ZBTB20 is required for anterior pituitary development and lactotrope specification [PDF]

, 2016
The anterior pituitary harbours five distinct hormone-producing cell types, and their cellular differentiation is a highly regulated and coordinated process.
Zhang, Weiping J., Xie, Zhifang, Cai, Jiao, Chen, Yu-Xia, Ma, Xianhua, Luan, Jing, Cao, Yi, Zhang, Hai, Zhu, Xiaotong, Shi, Guang-Xia, Shi, Yuguang, Yang, Rui, Liu, An-Jun, Grusby, Michael, Cao, Dongmei, Zou, Dajin, Cao, Xuetao   +16 more
core   +1 more source

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

Italian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni, S. Motta, N. Masera, S. Gasperini, A. Rovelli, R. Parini   +5 more
doaj   +1 more source

Description of the skull, braincase, and dentition of Moschognathus whaitsi (Dinocephalia, Tapinocephalia), and its palaeobiological and behavioral implications

The Anatomical Record, Volume 309, Issue 7, Page 1713-1748, July 2026.
Abstract A subadult Moschognathus whaitsi from the Eastern Cape Province, South Africa, was scanned using synchrotron radiation X‐ray computed tomography (SRXCT). Its subadult state allowed the cranial bones and teeth to be identified and individually reconstructed in 3D.
Tristen Lafferty, Luke A. Norton, Aliénor Duhamel, Julien Benoit   +3 more
wiley   +1 more source

Evaluation of Haemato‐Biochemical and Physiological Parameters of Different Dairy Breeds During the Dry and Wet Seasons in Central Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
The study found that Borana, Jersey and cross‐bred dairy cows in central Ethiopia are well‐adapted to the local climate, with haemato‐biochemical and physiological parameters remaining within normal reference ranges despite significant seasonal variations.
Teshome Gemechu, Mitiku Eshetu, Yesihak Yusuf Mummed, Ulfina Galmessa, Aemiro Kehaliew   +4 more
wiley   +1 more source

Single‐nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Gonadotropin‐releasing hormone (GnRH) is a central regulator of vertebrate reproduction regulating pituitary gonadotropins. In zebrafish, GnRH3 serves as the hypophysiotropic isoform. Its neurons develop by migrating from the nasal placode to the hypothalamus, forming several distinct subpopulations along the migratory path.
Yalong Sun, Matan Golan, Yonathan Zohar, Xiaoxuan Fan, Nilli Zmora   +4 more
wiley   +1 more source

Decreased lifespan in female "Munchkin" actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity [PDF]

, 2022
In laboratory mice, pituitary dwarfism caused by genetic reduction or elimination of the activity of growth hormone (GH) significantly extends lifespan. The effects of congenital pituitary dwarfism on human longevity are not well documented.
Ungvari, Zoltan, Tabak, Adam G, Sonntag, William E, Austad, Steven N, Fazekas-Pongor, Vince, Szarvas, Zsofia, Fekete, Monika, Peterfi, Anna, Csiszar, Anna, Major, David   +9 more
core  

TG Nonsense Variant in Dwarf Rottweiler Dogs

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT We identified a dwarfism syndrome in six Rottweiler dogs characterized by reduced height and body weight; limb deformities, shortening of the tail and abnormally thick skin in puppies; developmental delays, pain and non‐goitrous hypothyroidism. Histological examination of the thyroid gland revealed severe chronic diffuse bilateral atrophy with
Marie Abitbol, Michaela Drögemüller, Cleo Schwarz, Etienne Furthner, Eva Dervas, Felicitas S. Boretti, Nadja S. Sieber‐Ruckstuhl, Caroline Dufaure de Citres, Chloé Pauchard, Vidhya Jagannathan, Tosso Leeb   +10 more
wiley   +1 more source