Results 41 to 50 of about 7,016 (204)

Partial loss of function of the GHRH Receptor leads to mild Growth Hormone Deficiency [PDF]

open access: yes, 2016
OBJECTIVE: Recessive mutations in GHRHR are associated with severe isolated growth hormone deficiency (IGHD), with a final height in untreated patients of 130 cm ± 10 cm (-7.2 ± 1.6 SDS; males) and 114 ± 0.7 cm (-8.3 ± 0.1 SDS; females).
Alatzoglou, K S   +7 more
core   +2 more sources

Nanismo hipofisário em um canino: achados clínicos e laboratoriais Pituitary dwarfism in a canine: clinical and laboratorial findings

open access: yesCiência Rural, 1995
Relata-se um caso de nanismo hipofisário em um canino da raça Pastor Alemão, fêmea, com 14 meses de idade. Descreve-se sinais clínicos e dosagem das concentrações plasmáticas de hormônio do crescimento (GH) antes e após a estimulação α-adrenι ...
Luiz Fernando Jantzen Gaspar   +1 more
doaj   +1 more source

Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy.
Chiara Rodaro   +3 more
doaj   +1 more source

The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]

open access: yes, 2016
Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea   +3 more
core   +2 more sources

Palaeopathology of human remains of the 1st century BC–3rd century AD from Armenia (Beniamin, Shirakavan I)

open access: yesAnthropological Review, 2015
The aim of this article was to document the pathology of the individuals from the archeological sites of Beniamin and Shirakavan I, Armenia, dated on the 1st century BC - 3rd century AD. The findings revealed that two groups differed in mean age at death
Khudaverdyan Anahit Yu.
doaj   +1 more source

Role of cyclic AMP in the control of cell-specific gene expression [PDF]

open access: yes, 1993
Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael   +3 more
core   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

open access: yesIntegrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

open access: yesItalian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni   +5 more
doaj   +1 more source

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]

open access: yes, 2017
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J   +6 more
core   +3 more sources

Nonapeptide cell size differs between male morphs of the West African cichlid, Pelvicachromis pulcher

open access: yesJournal of Fish Biology, EarlyView.
Abstract Alternative male morphs are found in many species of fishes. These morphs often differ in suites of social behaviours, such as aggression and territoriality, associated with alternative reproductive tactics. Such consistent morph‐typical behavioural profiles suggest common differences in underlying neuroendocrine mechanisms.
Adam R. Reddon   +2 more
wiley   +1 more source

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