Treatment of atrichia pubis in adolescent girls with pituitary dwarfism [PDF]
, 1996 Five girls with multiple pituitary insufficiency and atrichia pubis, aged 14 to 22 years, were instructed to apply 5% testosterone undecanoate cream on the pubic area twice daily, Pubic hair development became noticeable between days 15 and 20 of ...
Kakourou, T, DacouVoutetakis, C
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Zebrafish pit1 Mutants Lack Three Pituitary Cell Types and Develop Severe Dwarfism [PDF]
, 2004 The Pou domain transcription factor Pit-1 is required for lineage determination and cellular commitment processes during mammalian adenohypophysis development. Here we report the cloning and mutational analysis of a pit1 homolog from zebrafish.
Nica, G. +3 more
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An animal model of combined pituitary hormone deficiency disease [PDF]
, 2010 LHX3 is a LIM-homeodomain transcription factor that has essential roles in pituitary and nervous system development in mammals. Children who are homozygous for recessive mutations in the LHX3 gene present with combined pituitary hormone deficiency ...
Colvin, Stephanie C. +1 more
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Erratum to prostate biopsy free system for laparoscopic radical prostatectomy in a pituitary dwarfism: a case report. [PDF]
Transl Androl Urol, 2021 Editorial Office.
europepmc +1 more source
Purification and cultivation of human pituitary growth hormone secreting cells [PDF]
, 1979 Efforts were directed towards maintenance of actively secreting human pituitary growth hormone cells (somatotrophs) in vitro. The production of human growth hormone (hGH) by this means would be of benefit for the treatment of certain human hypopituitary ...
Hymer, W. C.
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Hypothalamic-Pituitary Functions in Patients with Idiopathic Pituitary Dwarfism
Endocrinologia Japonica, 1975 To investigate hypothalamic-pituitary functions and the primary site of the lesion in idiopathic pituitary dwarfism, various pituitary function tests, especially the pituitary hormone responses to the hypophysiotropic hormones were studied in 23 patients with idiopathic pituitary dwarfism.
DEMURA, REIKO +7 more
openaire +3 more sources
Economic and social aspects of pituitary dwarfism treatment with recombinant growth hormone [PDF]
, 2017 Rationale. Pituitary dwarfism is an orphan disease requiring pathogenetic treatment. The domestic literature lacks studies devoted to the medical and economic effectiveness of treatment for growth hormone deficiency (GHD) using recombinant growth hormone
Maria V. Vorontsova +2 more
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Diffuse somatostatin-immunoreactive D-cell hyperplasia in the stomach and duodenum [PDF]
, 1986 This paper presents the first case of extensive, diffuse, somatostatin- immunoreactive D-cell hyperplasia in the human stomach and duodenum. It occurred in a 37-yr-old woman, who showed clinical signs of dwarfism, obesity, dryness of the mouth, and ...
Eisenmenger, Wolfgang +4 more
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A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia and obesity. [PDF]
, 2004 The SMA1-mouse is a novel ethyl-nitroso-urea (ENU)-induced mouse mutant that carries an a-->g missense mutation in exon 5 of the GH gene, which translates to a D167G amino acid exchange in the mature protein.
Fuchs, H. +10 more
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Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo [PDF]
, 2010 The etiology of most pediatric hormone deficiency diseases is poorly understood. Children with combined pituitary hormone deficiency (CPHD) have insufficient levels of multiple anterior pituitary hormones causing short stature, metabolic ...
Stephanie C. Colvin +4 more
core +1 more source