Results 71 to 80 of about 7,016 (204)

Metabolic and hemodynamic effects of the growth hormone system — insulin-like growth factor

Терапевтический архив, 2015
Significant congenital deficiency of growth factor (GF) results in pituitary nanism (dwarfism) and its substantial excess is accompanied by the development of gigantism or acromegaly.
T A Manhylova, N H Gafarova
doaj  

Juvenile hyposomatotropism in a Somali cat presenting with seizures due to intermittent hypoglycaemia

Journal of Feline Medicine and Surgery Open Reports, 2018
Case summary A 3-month-old intact male Somali cat was evaluated for a history of seizures, hypoglycaemia and mental dullness 4 weeks after being bitten in the head by a dog.
Maya Laura König, Diana Henke, Katja Adamik, Cristina Pérez Vera   +3 more
doaj   +1 more source

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

CD8+ T‐Cell Deletion Suppressed the Development of Injury‐Induced Experimental Neointimal Hyperplasia in Mice With or Without Chronic Stress

The FASEB Journal, Volume 39, Issue 18, 30 September 2025.
Graphical illustration of the mechanism of vascular remodeling under chronic stress. CD8+ T‐cell functions as an important mediator of injury‐related experimental neointimal hyperplasia via the modulation of inflammation, proteolysis and proliferation that is mediated by the IFN‐γ/AT1R‐galactin‐3 and mTOR/Akt‐p38MAPK axes.
Jingyuan Jin, Meiling Piao, Xianji Piao, Shangzhi Shu, Longguo Zhao, Zhibo Wang, Xueling Yue, Jinshun Piao, Xianglan Jin, Lina Hu, Yongshan Nan, Xian Wu Cheng   +11 more
wiley   +1 more source

Pituitary function in 8 patients with familial pituitary dwarfism

Pediatric Research, 1978
Pituitary function was evaluated in four pairs of familial pituitary dwarfs (two sisters, 28 and 20 years old, two brothers 15 and 10 years old, one girl 19 years old and her brother 7 years old, and one girl 9 years old and her brother 3 6/12 years old), who all proved to have multiple pituitary hormone deficiency (MPHD), in order to find out whether ...
BATRINOS, ML, PITOULIS, S, ANOUSAKIS, C, KOUTSILIERIS, MN, PANITSAFAFFLIA, C, ORPHANOS, SE   +5 more
openaire   +3 more sources

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

MedComm, Volume 6, Issue 9, September 2025.
This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily
Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu   +7 more
wiley   +1 more source

Metabolic Factors Related to Interpersonal Dysfunction in Acromegaly: A Nationwide Cross‐Sectional Study in China

CNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
Metabolic and physical factors—specifically frontal bossing, cardiovascular comorbidities, and elevated preoperative GH levels—are independent predictors of severe interpersonal dysfunction in Chinese patients with acromegaly. These findings underscore the need for integrating systematic psychosocial screening into routine neuroendocrine management to ...
Shashi Kiran Tagilapalli, Zongming Wang, Yuechu Lucinda Lu, Guofeng Zhang, Weijie Su, Zhentian Wu, Jiaming Wang, Qing Rao, Haijun Wang, Dongsheng He, Yonggao Mou, Shun Yao, Yanmei Tie, Wenli Chen   +13 more
wiley   +1 more source

Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia [PDF]

, 2018
Alterations in dopamine neurotransmission are generally associated with diseases such as attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD).
Anna Poleggi, Damiana Leo, Enrico Alleva, Francesca Zoratto, Giovanni Laviola, Luca Cerniglia, Raul R. Gainetdinov, Raul R. Gainetdinov, Renata Tambelli, Silvia Cimino, Stefano Cinque, Stefano Cinque, Walter Adriani, Walter Adriani   +13 more
core   +2 more sources

Beyond the Binary: Controlling Natural Sex‐Change in Hermaphroditic Fishes

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Sex‐change in hermaphroditic fishes is a complex but natural biological phenomenon that has significant implications for aquaculture fingerling production, selective breeding, and grow‐out. Understanding the physiological, endocrinological, and molecular pathways underlying hermaphroditism in fishes offers unique opportunities to manipulate ...
Roni Chandra Mondal, Jarrod L. Guppy, Maria A. Villacis‐Escobar, Dean R. Jerry   +3 more
wiley   +1 more source

Evaluation and Diagnostic Potential of Serum Ghrelin in Feline Hypersomatotropism and Diabetes Mellitus [PDF]

, 2015
BACKGROUND: Ghrelin is a growth hormone secretagogue. It is a potent regulator of energy homeostasis. Ghrelin concentration is down‐regulated in humans with hypersomatotropism (HS) and increases after successful treatment. Additionally, ghrelin secretion
Appleton, Barkan, Bedendi, Belsito, Berg, Bhatti, Brearley, Briatore, Cappiello, Cummings, Dezaki, Dunning, Erdmann, Feldman, Freda, Gelling, Ida, Jenkins, Jensen, Kawamata, Kojima, Kojima, Kozakowski, Krzyzanowska-Świniarska, Martin, McLaughlin, Meij, Natalucci, Niessen, Niessen, Niessen, Niessen, Peino, Pöykkö, Reusch, Roemmler, Saad, Sofer, Soriano-Guillén, Takaya, Tschuor, Ueno, Yada   +42 more
core   +2 more sources