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Stimulation of luteinizing hormone release from chicken pituitary cells by analogues of luteinizing hormone-releasing hormone

General and Comparative Endocrinology, 1977
The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
R C, Bonney, F J, Cunningham
openaire   +2 more sources

Cortisol inhibition of growth hormone-releasing hormone-stimulated growth hormone release from cultured sheep pituitary cells

Journal of Endocrinology, 1994
Abstract Cortisol inhibits growth hormone (GH) release in short-term culture and is stimulatory in long-term cultures of rat and human pituitary cells. This study sought to determine the in vitro effects of cortisol on GH release and the signal transduction pathways mediating the effects of cortisol on GH release from cultured ovine ...
J L, Sartin   +4 more
openaire   +2 more sources

Quantitative immunocytochemistry of pituitary receptors for luteinizing hormone-releasing hormone

Cell and Tissue Research, 1975
In Araldite sections of male rat pituitaries, stained after embedding by the unlabeled antibody enzyme method with antisera to native luteinizing hormone-releasing hormone (LH-RH) or LH-RH azo-conjugated to bovine serum albumin, localization is confined mainly to the interior of the large, and to a lesser extent to that of the small, secretion granules
L A, Sternberger, J P, Petrali
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Selectivity of Melatonin Pituitary Inhibition for Luteinizing Hormone-Releasing Hormone

Neuroendocrinology, 1982
The pineal indole melatonin suppresses the neonatal rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH) responses to LH-releasing hormone (LHRH), as shown in previous studies from this laboratory. We show in this study that the melatonin inhibition is a selective effect and is not due to general inhibition of pituitary function.
J E, Martin, C, Sattler
openaire   +2 more sources

Growth hormone-releasing hormone transcripts in human pituitary adenomas.

The Journal of Clinical Endocrinology & Metabolism, 1992
We have investigated the possibility that local production of GHRH within the adenohypophysis could be an aetiological factor in the development of human pituitary somatotroph and other tumours. We examined 51 human pituitary adenomas for GHRH transcripts using in situ hybridization histochemistry.
A, Levy, S L, Lightman
openaire   +3 more sources

Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis

Trends in Endocrinology & Metabolism, 2002
Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical ...
Lawrence A, Frohman, Rhonda D, Kineman
openaire   +2 more sources

Sexual dimorphic porcine pituitary response to growth hormone-releasing hormone

Domestic Animal Endocrinology, 1990
The aim of this study was to compare growth hormone (GH) response of barrows and gilts to porcine growth hormone-releasing hormone (pGRH) at the pituitary level. Anterior pituitary cells from barrows and gilts responded to pGRH in a dose-dependent manner.
M L, Heiman   +3 more
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Prolactin Inhibits Pituitary Luteinizing Hormone-Releasing Hormone Receptors in the Rat

Endocrinology, 1982
Pituitary LHRH receptors were studied in intact immature and mature female rats as well as in adult castrated animals of both sexes under experimental conditions leading to marked alterations of plasma PRL levels. Implantation of three anterior pituitary glands under the kidney capsule on the morning of estrus prevented the increase in pituitary LHRH ...
MARCHETTI, Bianca Maria, Labrie F.
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STIMULATION OF GROWTH HORMONE RELEASE BY LUTEINIZING HORMONE‐RELEASING HORMONE AND MELANOCYTE‐STIMULATING HORMONE‐RELEASE INHIBITING HORMONE IN THE HYPOPHYSECTOMIZED RAT BEARING AN ECTOPIC PITUITARY

Clinical Endocrinology, 1976
SummaryIntrajugular administration of LHRH (0.6 and 1.2 μg) in hypophysectomized rats which received renal grafts of anterior pituitary induced a small but significant rise in plasma GH 5 and 10 min post‐treatment. LHRH, at the same dose levels, was ineffective in weight‐matched intact controls.
Panerai A. E.   +5 more
openaire   +3 more sources

Galanin modulates pituitary hormones release.

Neuro endocrinology letters, 2006
Galanin and its receptors are widely distributed within the central and peripheral nervous system, especially in hypothalamus including preoptic area, paraventricular nucleus (PVN), supraoptic nucleus (SON) and median eminence. Galanin plays an important role in the control of food intake, energy expenditure, reproduction, water balance and various ...
Agnieszka, Baranowska-Bik   +5 more
openaire   +1 more source

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