Results 181 to 190 of about 68,285 (212)
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Pituitary adenomas in mice transgenic for growth hormone-releasing hormone
Endocrinology, 1992It has been shown that mice transgenic for human GH-releasing hormone (GRH) develop hyperplasia of pituitary somatotrophs, lactotrophs, and mammosomatotrophs, cells capable of producing both GH and PRL, by 8 months of age. We now report that GRH transgenic mice 10-24 months of age develop pituitary adenomas, which we characterized by histology ...
Asa, S L +6 more
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Diabetes, 1975
Impaired fertility and menstrual disturbances are common in diabetes mellitus. In order to study the effect of diabetes on gonadotropin secretion by the pituitary gland, twenty premenopausal diabetic females and seven diabetic males were investigated using luteinizing hormone-releasing hormone (LH-RH).
L A, Distiller +3 more
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Impaired fertility and menstrual disturbances are common in diabetes mellitus. In order to study the effect of diabetes on gonadotropin secretion by the pituitary gland, twenty premenopausal diabetic females and seven diabetic males were investigated using luteinizing hormone-releasing hormone (LH-RH).
L A, Distiller +3 more
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Follistatin specifically inhibits pituitary follicle stimulating hormone release invitro
Biochemical and Biophysical Research Communications, 1987Two forms of purified follistatin, a single-chain polypeptide of mol wt 35,000 (35 Kd) protein, and a related molecule of mol wt 32,000 (32 Kd), which differs from the 35 Kd form in glycosylation or carboxyl terminal truncation, specifically inhibit the release of immunoreactive FSH by primary cultures of rat pituitary cells.
S Y, Ying +8 more
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European Journal of Pharmacology, 1991
Enhancement of the amphiphilic alpha-helical properties of the central and C-terminal regions of growth hormone-releasing hormone (GRH) by substitution with helix-favouring amino acids, particularly Ala, can result in significant improvements in GH-releasing potencies using monolayer cultures of rat pituitary cells, a system which reflects analogue ...
D H, Coy, S J, Hocart, W A, Murphy
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Enhancement of the amphiphilic alpha-helical properties of the central and C-terminal regions of growth hormone-releasing hormone (GRH) by substitution with helix-favouring amino acids, particularly Ala, can result in significant improvements in GH-releasing potencies using monolayer cultures of rat pituitary cells, a system which reflects analogue ...
D H, Coy, S J, Hocart, W A, Murphy
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Molecular and Cellular Endocrinology, 1978
A method has been developed for disaggregating porcine anterior pituitary tissue and for providing dissociated preparations which have good, stable viability in culture. The secretory capacity for these preparations in terms of their ability to release luteinizing hormone in response to luteinizing hormone-releasing hormone has been documented in ...
A M, Walker, C R, Hopkins
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A method has been developed for disaggregating porcine anterior pituitary tissue and for providing dissociated preparations which have good, stable viability in culture. The secretory capacity for these preparations in terms of their ability to release luteinizing hormone in response to luteinizing hormone-releasing hormone has been documented in ...
A M, Walker, C R, Hopkins
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Mechanisms by which Somatostatin Inhibits Pituitary Hormone Release
1987Since somatostatin inhibits secretion in a wide variety of target cells, studies probing its mechanism of action have focused on the involvement of the two intracellular messengers known to regulate secretory processes: cyclic AMP and calcium (see reviews 1–5).
Agnes Schonbrunn, Bruce D. Koch
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9. Thymic hormone stimulation of pituitary hormone release
Journal of Neuroimmunology, 1987B.L. Spangelo, R.M. MacLeod
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Aggressive pituitary tumours and pituitary carcinomas
Nature Reviews Endocrinology, 2021Pr Gerald Raverot +2 more
exaly
Growth hormone-releasing hormone receptor mRNA in acromegalic pituitary tumors.
The American journal of pathology, 1997The growth hormone (GH)-releasing hormone receptor (GHRH-R) has been recently cloned and found to be a member of a new family of seven transmembrane receptors that includes secretin, vasoactive intestinal peptide, calcitonin, and corticotropin-releasing factor.
M B, Lopes +3 more
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