Results 201 to 210 of about 741,920 (302)

Weight Regain After Incretin Treatment: The Lean Mass Deficit Hypothesis and a Role for Testosterone Combination Therapy in Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1RA and triple (GIP)/GLP‐1RA/glucagon agonists achieve placebo‐subtracted weight loss of 15% to 22%. Their long‐term value depends on how well the weight loss is maintained and on the composition of weight loss, not only
Michael Zitzmann, Zsolt Bosnyak, Richard Jones, Monica Caliber   +3 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics and Exploratory Pharmacodynamics of Melanin‐Concentrating Hormone Receptor‐1 Antagonist RGH‐706 in Healthy and Overweight or Obese Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This Phase 1 program evaluated the safety, tolerability, pharmacokinetics and exploratory pharmacodynamics of the novel melanin‐concentrating hormone receptor‐1 antagonist RGH‐706. Methods Study A was a first‐in‐man, randomized trial comprising a double‐blind, placebo‐controlled single‐ascending‐dose part (0.1–162.5 mg) and a two‐way ...
Thomas Brevig, Borbála Szepes, Zsófia Borbála Dombi, Gabriella Magyar, Zoltán Juhász, Margit Kapás, Éva Cseh, Zsuzsa Hegedűs, Tibor Farkas, Zsuzsanna Kiss, Balázs Szatmári   +10 more
wiley   +1 more source

Macrohormones in endocrinology: prevalence, clinical impact, and diagnostic approaches. [PDF]

Front Endocrinol (Lausanne)
Bronisławska A, Cyran-Stańczak O, Bronisławski R, Solecka A, Berlińska A, Świątkowska-Stodulska R, Jendrzejewski JP.   +6 more
europepmc   +1 more source

Dental resin composites generate microparticles and impact on gingival keratinocytes—In vitro study

European Journal of Oral Sciences, EarlyView.
Abstract Along with our increased understanding of the spread of microplastic pollution, the awareness of microparticle release from medical and dental materials has increased. Still, their effects on human health are largely unknown. As the use of resin composite materials in dentistry continues to increase, it is essential to understand the formation
Ella Pullinen, Saara V. Sirkiä, Johan Nyman, Pekka K. Vallittu, Vuokko Loimaranta   +4 more
wiley   +1 more source

The Neuroendocrine-Cardiovascular Axis in Chronic Kidney Disease: The Role of Prolactin and Gonadal Dysfunction.

Cardiorenal Med
Barbera V, Di Lullo L, Bellasi A, D'Elia L, Villani A, Peverini P, Franculli A.   +6 more
europepmc   +1 more source

Case Report: Development of a thyrotropinoma in a patient with thyroid hemiagenesis. [PDF]

Front Endocrinol (Lausanne)
Rozenek EB, Gurnell M, Kunicki J, Maksymowicz M, Korbonits M, Zgliczyński W, Stelmachowska-Banaś M.   +6 more
europepmc   +1 more source

The Company We Keep: Effects of Different Social Environments on Male Guinea Pig Behaviour and Hormones Over the Course of the Ontogeny

Ethology, EarlyView.
To examine how their behaviour and hormones change over different life phases, male guinea pigs experienced two different social environments from juvenility to adulthood. Only one environment contained social stimulation by unfamiliar conspecifics. Although no differences in testosterone and cortisol concentrations were found, it was interesting that ...
Maximilian Baldy, Sylvia Kaiser
wiley   +1 more source

Syndrome differentiation and treatment of pediatric central precocious puberty: role of the spleen-kidney axis. [PDF]

Front Immunol
Luo Y, Huang C, Lu Y, He J, Chen H, Yang J.   +5 more
europepmc   +1 more source

From Social Experience to Social Behaviour: Hormonal and Behavioural Phenotypes During Adolescence in Male Guinea Pigs

Ethology, EarlyView.
To investigate how different social environments during adolescence influence hormones and behaviour, adolescent male guinea pigs were pair‐housed with a female either with or without additional social stimulation through repeated brief encounters with unfamiliar conspecifics.
Melanie Gleske, Carolin Mundinger, S. Helene Richter, Sylvia Kaiser   +3 more
wiley   +1 more source

Extracellular Matrix-Mediated Neuroendocrine Control of the Thymus.

Neuroimmunomodulation
Brito-Moreira J, Herculano EA, Savino W.
europepmc   +1 more source