Results 211 to 220 of about 32,431 (267)

Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis

Trends in Endocrinology & Metabolism, 2002
Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical ...
Lawrence A, Frohman, Rhonda D, Kineman
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Selectivity of Melatonin Pituitary Inhibition for Luteinizing Hormone-Releasing Hormone

Neuroendocrinology, 2008
The pineal indole melatonin suppresses the neonatal rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH) responses to LH-releasing hormone (LHRH), as shown in previous studies from this laboratory. We show in this study that the melatonin inhibition is a selective effect and is not due to general inhibition of pituitary function.
J E, Martin, C, Sattler
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Quantitative immunocytochemistry of pituitary receptors for luteinizing hormone-releasing hormone

Cell and Tissue Research, 1975
In Araldite sections of male rat pituitaries, stained after embedding by the unlabeled antibody enzyme method with antisera to native luteinizing hormone-releasing hormone (LH-RH) or LH-RH azo-conjugated to bovine serum albumin, localization is confined mainly to the interior of the large, and to a lesser extent to that of the small, secretion granules
L A, Sternberger, J P, Petrali
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Stimulation of luteinizing hormone release from chicken pituitary cells by analogues of luteinizing hormone-releasing hormone

General and Comparative Endocrinology, 1977
The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
R C, Bonney, F J, Cunningham
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Dissociation of the porcine anterior pituitary: The kinetics of luteinizing hormone release in response to luteinizing hormone-releasing hormone

Molecular and Cellular Endocrinology, 1978
A method has been developed for disaggregating porcine anterior pituitary tissue and for providing dissociated preparations which have good, stable viability in culture. The secretory capacity for these preparations in terms of their ability to release luteinizing hormone in response to luteinizing hormone-releasing hormone has been documented in ...
A M, Walker, C R, Hopkins
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Factors Influencing Pituitary Glycogen Metabolism and Gonadotropic Hormone Release. I. Luteinizing Hormone-Releasing Hormone

Fertility and Sterility, 1974
The way in which luteinizing hormone (LH) and follicle stimulating h ormone (FSH) are related to pituitary glycogen metabolism is investigated by measuring pituitary glycogen content and the activity of glycogen synthetase and glycogen phosphorylase in LH-releasing hormone (LH-RH) treated rat pituitaries.
T, Makino, L M, Demers, R O, Greep
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Effect of hydrocortisone on the pituitary response to growth hormone releasing hormone

Psychopharmacology, 2000
In depression, the growth hormone (GH) response to clonidine and L-tryptophan (L-TRP) is reduced, suggesting reduced alpha2-adrenergic and serotonin (5-HT)1A receptor function. Pretreatment with hydrocortisone (100 mg, orally 11 h before) also blunts the GH response to L-TRP.
S, Watson, R J, Porter, A H, Young
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Immunocytochemistry of a ?private? luteinizing-hormone-releasing hormone system in the pituitary

Cell and Tissue Research, 1984
Immunocytochemistry of paraffin sections of Bouin-fixed rat pituitaries with antiserum to luteinizing-hormone-releasing hormone (LHRH) revealed two types of cells. Type I cells exhibit granular staining throughout their cytoplasm. The immunoreactivity of type II cells is confined to a much smaller area of the cytoplasm.
J Y, Li, R J, Knapp, L A, Sternberger
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Prolactin Inhibits Pituitary Luteinizing Hormone-Releasing Hormone Receptors in the Rat

Endocrinology, 1982
Pituitary LHRH receptors were studied in intact immature and mature female rats as well as in adult castrated animals of both sexes under experimental conditions leading to marked alterations of plasma PRL levels. Implantation of three anterior pituitary glands under the kidney capsule on the morning of estrus prevented the increase in pituitary LHRH ...
MARCHETTI, Bianca Maria, Labrie F.
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Growth hormone releasing factor increases growth hormone release from MtTW15 pituitary tumors

Brain Research, 1984
The MtTW15 pituitary tumor secretes growth hormone and prolactin. Perfusion of these dispersed MtTW15 tumor cells with 10 nM growth hormone releasing factor (GRF) increases growth hormone release without affecting prolactin release. This effect is dose-dependent between 0.001 and 0.1 nM and is blocked by 100 nM somatostatin. These findings suggest that
A M, Judd, R M, MacLeod
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