Results 291 to 300 of about 248,144 (357)

Growth hormone-releasing hormone and pituitary somatotrope proliferation.

Minerva endocrinologica, 2003
Growth hormone-releasing hormone (GHRH) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development. Decreased GHRH secretion and/or action leads to impairment of this process and somatotrope hypoplasia in both humans and experimental animals.
L A, Frohman, R D, Kineman
openaire   +1 more source

Extra-pituitary inhibition of testicular function by luteinising hormone releasing hormone

Nature, 1979
Luteinising hormone releasing hormone (LHRH), produced by the hypothalamus, stimulates gonadotropin production by the pituitary1–3. Paradoxically, chronic treatment with large doses of LHRH or its agonists causes a decline in testicular steroidogenesis and testicular LH/human chorionic gonadotropin (hCG) receptors; they also cause a decrease in the ...
A J, Hsueh, G F, Erickson
openaire   +2 more sources

Extra-pituitary action of luteinizing hormone releasing hormone on intraocular pressure

Current Eye Research, 1988
Luteinizing hormone releasing hormone (LHRH) given intraventricularly caused a delayed, significant decrease of intraocular pressure (IOP) in adult female rabbits for a prolonged period, but only elevated plasma gonadotropins for a few hrs. Intravenous injections of LHRH caused a similar elevation of plasma gonadotropins without any effect on IOP.
J H, Liu, A C, Dacus
openaire   +2 more sources

Pituitary adenomas in mice transgenic for growth hormone-releasing hormone

Endocrinology, 1992
It has been shown that mice transgenic for human GH-releasing hormone (GRH) develop hyperplasia of pituitary somatotrophs, lactotrophs, and mammosomatotrophs, cells capable of producing both GH and PRL, by 8 months of age. We now report that GRH transgenic mice 10-24 months of age develop pituitary adenomas, which we characterized by histology ...
Asa, S L, Kovacs, K, Stefaneanu, L, Horvath, E, Billestrup, Nils, Gonzalez-Manchon, C, Vale, W   +6 more
openaire   +4 more sources

Pituitary responsiveness to luteinizing hormone-releasing hormone in insulin-dependent diabetes mellitus

Diabetes, 1975
Impaired fertility and menstrual disturbances are common in diabetes mellitus. In order to study the effect of diabetes on gonadotropin secretion by the pituitary gland, twenty premenopausal diabetic females and seven diabetic males were investigated using luteinizing hormone-releasing hormone (LH-RH).
L A, Distiller, J, Sagel, J E, Morley, H C, Seftel   +3 more
openaire   +2 more sources

Follistatin specifically inhibits pituitary follicle stimulating hormone release invitro

Biochemical and Biophysical Research Communications, 1987
Two forms of purified follistatin, a single-chain polypeptide of mol wt 35,000 (35 Kd) protein, and a related molecule of mol wt 32,000 (32 Kd), which differs from the 35 Kd form in glycosylation or carboxyl terminal truncation, specifically inhibit the release of immunoreactive FSH by primary cultures of rat pituitary cells.
S Y, Ying, A, Becker, G, Swanson, P, Tan, N, Ling, F, Esch, N, Ueno, S, Shimasaki, R, Guillemin   +8 more
openaire   +2 more sources

Human growth hormone-releasing hormone analogues with much improved in vitro growth hormone-releasing potencies in rat pituitary cells

European Journal of Pharmacology, 1991
Enhancement of the amphiphilic alpha-helical properties of the central and C-terminal regions of growth hormone-releasing hormone (GRH) by substitution with helix-favouring amino acids, particularly Ala, can result in significant improvements in GH-releasing potencies using monolayer cultures of rat pituitary cells, a system which reflects analogue ...
D H, Coy, S J, Hocart, W A, Murphy
openaire   +2 more sources

Dissociation of the porcine anterior pituitary: The kinetics of luteinizing hormone release in response to luteinizing hormone-releasing hormone

Molecular and Cellular Endocrinology, 1978
A method has been developed for disaggregating porcine anterior pituitary tissue and for providing dissociated preparations which have good, stable viability in culture. The secretory capacity for these preparations in terms of their ability to release luteinizing hormone in response to luteinizing hormone-releasing hormone has been documented in ...
A M, Walker, C R, Hopkins
openaire   +2 more sources

THE INTERACTION OF GROWTH HORMONE RELEASING HORMONE WITH OTHER HYPOTHALAMIC HORMONES ON THE RELEASE OF ANTERIOR PITUITARY HORMONES

Clinical Endocrinology, 1986
B. Looij, A. Kruseman, A. Mudde, M. Frölich, G. Piaditis, S. Hodgkinson, C. McLean, A. Grossman, D. Coy, L. Rees, P. Lowry, G. Besser   +11 more
semanticscholar   +1 more source

Reproductive hormones in aging men. II. Basal pituitary gonadotropins and gonadotropin responses to luteinizing hormone-releasing hormone.

Journal of Clinical Endocrinology and Metabolism, 1982
S. Harman, P. Tsitouras, P. Costa, M. Blackman   +3 more
semanticscholar   +1 more source