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Molecular, functional, and histopathological classification of the pituitary neuroendocrine neoplasms

Brain Tumor Pathology, 2021
In 2017, WHO published an updated classification of the pituitary adenomas according to the lineages defined by the transcription factors, PIT1, SF1 and TPIT. Nomenclature of the pituitary tumors follows the mature cell types such as somatotroph (GH), lactotroph (LH), thyrotroph, corticotroph, and gonadotroph (FSH, LH).
C. Inomoto   +6 more
semanticscholar   +4 more sources

Biomarkers of Pituitary Neoplasms: A Review (Part II) [PDF]

open access: possibleNeurosurgery, 2010
Several new markers have shown a capacity to predict the clinicopathological behavior of pituitary neoplasms; these markers have shown potential to correlate with tumor subtype and size and patient age and sex. These various markers are involved in a host of cellular functions, including cell-cycle progression, cell proliferation, apoptosis, cell ...
F. Salehi   +5 more
semanticscholar   +3 more sources

Ki-67 in pituitary neoplasms: a review--part I.

Neurosurgery, 2009
KI-67, A MARKER of cellular proliferation, has been studied extensively in pituitary neoplasia. It is of relevance to various clinicopathological parameters, including tumor subtype, size, invasiveness, and recurrence, as well as patient age and sex ...
F. Salehi   +5 more
semanticscholar   +5 more sources

Psychological changes associated with giant pituitary neoplasms.

Archives of Neurology And Psychiatry, 1955
Although nearly 600 articles concerning pituitary adenomas and craniopharyngiomas have been listed in the Quarterly Cumulative Index Medicus since its first volume, in 1916, only 13 are primarily concerned with the psychological changes which these ...
J. White, S. Cobb
semanticscholar   +4 more sources

Pituitary Neoplasms in two Horses

Zentralblatt für Veterinärmedizin Reihe A, 2010
Summary Two pituitary adenomas in older geldings are described: a)  a chromophobe adenoma with severe acute hemorrhages among the neoplastic cells and b)  an adenoma originating from the pars intermedia with a lesser degree of disseminated
H. Urman, H. Ozcan, S. Tekeli
semanticscholar   +3 more sources

Ultrastructure of spontaneous pituitary neoplasms in the rat.

Journal of Comparative Pathology, 1980
Abstract Spontaneous pituitary neoplasms of 19 old Sprague-Dawley rats were examined by electron microscopy. The ultrastructure suggested that the chromophobe adenomata were derived mainly from mammotropic cells and that they were functionally active.
S. Majeed, C. Gopinath, G. Magnusson
semanticscholar   +4 more sources

Immunohistochemical expression of nestin in the non-tumorous hypophysis and in pituitary neoplasms

Acta Neuropathologica, 2006
The aim of the present work was to investigate whether nestin, a member of the intermediate filament family, is immunohistochemically expressed in the non-tumoral human hypophysis and pituitary neoplasms. Twenty-three normal pituitaries and 125 pituitary neoplasms were included. The tissues were formalin-fixed and paraffin embedded.
F. Rotondo   +5 more
semanticscholar   +4 more sources

A proposed clinical classification for pituitary neoplasms to guide therapy and prognosis.

The Lancet Diabetes & Endocrinology
No comprehensive classification system that guides prognosis and therapy of pituitary adenomas exists. The 2022 WHO histopathology-based classification system can only be applied to lesions that are resected, which represent few clinically significant pituitary adenomas.
Ken K. Y. Ho   +12 more
semanticscholar   +3 more sources

Diagnosis and Management of Pituitary Adenomas: A Review.

Journal of the American Medical Association (JAMA), 2023
Importance Pituitary adenomas are neoplasms of the pituitary adenohypophyseal cell lineage and include functioning tumors, characterized by the secretion of pituitary hormones, and nonfunctioning tumors.
N. Tritos, K. Miller
semanticscholar   +1 more source

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