Results 61 to 70 of about 105,804 (267)

Application of 3D‐Slicer combined with 3D printing technology in training neurosurgery resident physicians' imaging spatial cognition and clinical reasoning: A self‐controlled before‐ and after‐study

Anatomical Sciences Education, EarlyView.
Abstract Neurosurgical residency training requires advanced spatial cognition and 3D anatomical understanding, which traditional methods often fail to adequately develop. This study evaluated a novel educational model integrating 3D Slicer and 3D printing technology to enhance imaging spatial cognition and clinical reasoning among neurosurgery ...
Li Xueyu, Fan Yuanxian, Chen Jiaxing, Li Chuanyu, Chen Yuanbiao, Huang Haineng, Huang Huadong, Luo Kunxiang, Wei Shiyin, Tan Rong   +9 more
wiley   +1 more source

Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/β-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors

Cellular Physiology and Biochemistry, 2018
Background/Aims: Long noncoding RNAs (lncRNAs) are critical regulators in various diseases including human cancer and could function as competing endogenous RNAs (ceRNAs) to regulate microRNAs (miRNAs).
Heyuan Wang, Guixia Wang, Yufei Gao, Conghai Zhao, Xiaoping Li, Fuqiang Zhang, Chunyan Jiang, Bing Wu   +7 more
doaj   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women

Acta Neuropathologica Communications
The incidence of pituitary adrenocorticotropic hormone (ACTH)-secreting PitNETs, commonly known as ACTH PitNETs, is significantly higher in females; however, the underlying causes for this gender disparity remain unclear.
Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu   +8 more
doaj   +1 more source

Carotid Endarterectomy Ameliorates Cognitive Impairment in Clinical and Experimental Unilateral Carotid Artery Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Carotid endarterectomy (CEA) is widely used to treat carotid artery stenosis (CAS). However, the effects of CEA on unilateral CAS‐induced cognitive impairment and the underlying mechanism remain poorly understood.
Yijun Cheng, Bin Chen, Miao Zhang, Zhenghong Chen, Mingjian Liu, Ziqian Zhang, Hao Tang, Dapeng Wang, Wenwen Lv, Biao Li, Yuting Dai, Hanbing Shang   +11 more
doaj   +1 more source

Tumor of the Pituitary Body [PDF]

The Journal of Nervous and Mental Disease, 1893
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openaire   +2 more sources

Developmental Morphometry of the Paranasal Sinuses in Subjects Aged 1–25 Years: A Computed Tomography Study

Clinical Anatomy, EarlyView.
ABSTRACT The present study aimed to evaluate the developmental morphometry of the paranasal sinuses using computed tomography (CT) in subjects aged 1–25 years and to characterize age‐related changes in sinus dimensions, volume, and surface area throughout childhood, adolescence, and young adulthood.
Ceyda Şevval Çetin, Aslıhan Artaş, Ali Atadağ, Ömer Faruk Cihan, Orhan Beger   +4 more
wiley   +1 more source

Biography as the Missing Variable in Drug Development: A Case for Bio‐Biographical Mechanistic Profiling

Clinical Pharmacology &Therapeutics, EarlyView.
Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley   +1 more source

An efficient deep learning model for brain tumour detection with privacy preservation

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Internet of medical things (IoMT) is becoming more prevalent in healthcare applications as a result of current AI advancements, helping to improve our quality of life and ensure a sustainable health system. IoMT systems with cutting‐edge scientific capabilities are capable of detecting, transmitting, learning and reasoning.
Mujeeb Ur Rehman, Arslan Shafique, Imdad Ullah Khan, Yazeed Yasin Ghadi, Jawad Ahmad, Mohammed S. Alshehri, Mimonah Al Qathrady, Majed Alhaisoni, Muhammad H. Zayyan   +8 more
wiley   +1 more source

Correlation between intrasellar pressure, pituitary adenoma invasiveness, pituitary dysfunction, and apoplexy

Frontiers in Endocrinology
BackgroundFew studies have reported the association between intrasellar pressure (ISP) and tumor invasiveness, hypopituitarism, or pituitary apoplexy in patients with pituitary adenomas.
Shan Xie, Shan Xie, Zhilin Shao, Dongqi Shao, Xialin Zheng, Huadong Tang, Yu Li, Renhao Zhang, Tianyang Wu, Hao Lang, Rui Xu, Chenxi Li, Hongwei Cheng, Zhiquan Jiang, Zhiquan Jiang   +14 more
doaj   +1 more source