Results 81 to 90 of about 3,259,919 (360)

Efficacy and safety of BRAF-MEK inhibitors in treatment of Chinese patients with papillary craniopharyngioma: A retrospective cohort study

Molecular Therapy: Oncology
Previous research supports the efficacy of BRAF-MEK inhibitor therapy for papillary craniopharyngiomas (PCPs). This retrospective study of 30 Chinese PCP patients evaluated tumor response and safety outcomes during treatment. All patients maintained 100%
Rui Han, Xiaorong Yan, Boyuan Yao, Boyu Cai, Nidan Qiao, Zengyi Ma, Zhen Ye, Xufang Gu, Zhao Ye, Buqing Liang, Zhengyuan Chen, Wenqiang He, Yifei Yu, Xiaoyun Cao, Haixia Cheng, Hong Chen, Yongfei Wang, Hongying Ye, Zhaoyun Zhang, Yao Zhao, Ruofan Huang, Qilin Zhang   +21 more
doaj   +1 more source

Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China

Chinese Neurosurgical Journal, 2020
Background Although the incidence and clinical manifestations of pituitary apoplexy were reported by a few researches, the results are not consistent.
Yao Li, Yuan Qian, Yisheng Qiao, Xiaoxiang Chen, Jiaotian Xu, Chao Zhang, Wei Wang, Junjun Li, Xingli Deng   +8 more
doaj   +1 more source

Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism [PDF]

, 2017
BACKGROUND: Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
Abraham, Berg, Bruns, Church, Colao, Colao, Combes, Cozzi, Dowling, Dunning, Feelders, Freda, Gadelha, Henry, Hofland, Hubina, Hussaini, Jaffe, Katznelson, Kurosaki, Lamb, Laron, Ma, Meij, Meij, Myers, Niessen, Niessen, Niessen, Patel, Petersenn, Peterson, Reubi, Reusch, Reusch, Sathyapalan, Schaefer, Scudder, Shanik, Slingerland, Slingerland, Theodoropoulou, Tyson, Zambre   +43 more
core   +2 more sources

A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A novel hybrid transfer learning approach for brain tumor classification achieves 99.47% accuracy using magnetic resonance imaging (MRI) images. By combining image preprocessing, ensemble deep learning, and explainable artificial intelligence (XAI) techniques like gradient‐weighted class activation mapping and SHapley Additive exPlanations (SHAP), the ...
Sadia Islam Tonni, Md. Alif Sheakh, Mst. Sazia Tahosin, Md. Zahid Hasan, Taslima Ferdaus Shuva, Touhid Bhuiyan, Muhammad Ali Abdullah Almoyad, Nabil Anan Orka, Md. Tanvir Rahman, Risala Tasin Khan, M. Shamim Kaiser, Mohammad Ali Moni   +11 more
wiley   +1 more source

Acute hypopituitarism associated with periorbital swelling and cardiac dysfunction in a patient with pituitary tumor apoplexy: a case report

Journal of Medical Case Reports, 2017
Background Pituitary tumor apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction in a preexisting pituitary adenoma. It typically manifests as an acute episode of headache, visual disturbance, mental status changes, cranial nerve ...
Nobumasa Ohara, Yuichiro Yoneoka, Yasuhiro Seki, Katsuhiko Akiyama, Masataka Arita, Kazumasa Ohashi, Kazuo Suzuki, Toshinori Takada   +7 more
doaj   +1 more source

Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease. [PDF]

, 2017
The CABLES1 cell cycle regulator participates in the adrenal-pituitary negative feedback, and its expression is reduced in corticotropinomas, pituitary tumors with a largely unexplained genetic basis.
Assié, Guillaume, Balsalobre, Aurelio, Bertherat, Jérôme, Chittiboina, Prashant, Dimopoulos, Aggeliki, Drouin, Jacques, Faucz, Fabio R, Gaillard, Stephan, Gam, Ryhem, Gauthier, Yves, Hernández-Ramírez, Laura C, Kay, Denise M, Lane, John, Lodish, Maya B, Mills, James L, Neou, Mario, Pankratz, Nathan, Stratakis, Constantine A, Trivellin, Giampaolo, Valdés, Nuria, Villa, Chiara   +20 more
core   +2 more sources

On‐Device Brain Tumor Classification from MR Images Using Smartphone

Advanced Intelligent Systems, EarlyView.
Herein, various deep learning models are trained for brain tumor classification task, and model performances are compared. The performance is further improved by using the proposed preprocessing algorithm before training. The MobileViT model, which is the best‐performing model in terms of balance between inference time and success rate, is integrated ...
Halil Ibrahim Ustun, Merve Bulbul, Gozde Yolcu Oztel, Veysel Harun Sahin   +3 more
wiley   +1 more source

Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors

Acta Neuropathologica Communications
We aimed to identify the druggable cell-intrinsic vulnerabilities and target-based drug therapies for PitNETs using the high-throughput drug screening (HTS) and genomic sequencing methods. We examined 9 patient-derived PitNET primary cells in HTS.
Yijun Cheng, Yuting Dai, Hao Tang, Xingyu Lu, Jing Xie, Wanqun Xie, Qianqian Zhang, Yanting Liu, Shaojian Lin, Hong Yao, Hanbing Shang, Kun Yang, Hongyi Liu, Xuefeng Wu, Jianming Zhang, Xun Zhang, Li Xue, Zhe Bao Wu   +17 more
doaj   +1 more source

Multi-Classification of Brain Tumor Images Using Deep Neural Network

IEEE Access, 2019
Brain tumor classification is a crucial task to evaluate the tumors and make a treatment decision according to their classes. There are many imaging techniques used to detect brain tumors.
Hossam H. Sultan, Nancy M. Salem, W. Al-Atabany   +2 more
semanticscholar   +1 more source

A case report of pituitary neuroendocrine tumor manifesting as severe conjunctival chemosis [PDF]

, 2023
Shun Yamamuro, Atsuo Yoshino, Takuma Nishide, Hiroshi Negishi, Takahiro Kumagawa   +4 more
openalex   +1 more source