Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza+4 more
wiley +1 more source
Chromogranin A in pituitary adenomas: immunohistochemical detection and plasma concentrations.
Forty one pituitary adenomas excised surgically were immunostained to reveal pituitary hormones and chromogranin A (CgA). In 23 patients, plasma CgA concentration was determined before surgery by ELISA method.
Jolanta Kunert-Radek+3 more
doaj +1 more source
Effects of perampanel on bone health in adult patients with epilepsy
Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu+8 more
wiley +1 more source
Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő+6 more
core
Activities of bone morphogenetic proteins in prolactin regulation by somatostatin analogs in rat pituitary GH3 cells [PDF]
Involvement of the pituitary BMP system in the modulation of prolactin (PRL) secretion regulated by somatostatin analogs, including octreotide (OCT) and pasireotide (SOM230), and a dopamine agonist, bromocriptine (BRC), was examined in GH3 cells.
Inagaki, Kenichi+8 more
core +1 more source
Development and Application of Polyphenols in Food: A Comprehensive Review
This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food. ABSTRACT This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food.
Yanpei Huang+7 more
wiley +1 more source
Understanding and treating ejaculatory dysfunction in men with diabetes mellitus
Abstract Diabetes mellitus is a rapidly rising metabolic disorder with important systemic complications. Global figures have demonstrated the prevalence of diabetes mellitus has almost quadrupled from 108 million in 1980 to 422 million in 2014, with a current prevalence of over 525 million.
Ankit Desai+4 more
wiley +1 more source
Detecting Glioma, Meningioma, and Pituitary Tumors, and Normal Brain Tissues based on Yolov11 and Yolov8 Deep Learning Models [PDF]
Accurate and quick diagnosis of normal brain tissue Glioma, Meningioma, and Pituitary Tumors is crucial for optimal treatment planning and improved medical results. Magnetic Resonance Imaging (MRI) is widely used as a non-invasive diagnostic tool for detecting brain abnormalities, including tumors.
arxiv
No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P.+3 more
core