British Journal of Pharmacology, EarlyView.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Slowly Progressive Secondary Adrenal Insufficiency Due to Pembrolizumab Administration in a Patient With a History of Pituitary Neuroendocrine Tumor [PDF]
Hiroyuki Ueda +6 more
openalex +1 more source
Genetic and Epigenetic Characterization of Growth Hormone–Secreting Pituitary Tumors [PDF]
, 2019 Niko Välimäki +6 more
openalex +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
British Journal of Pharmacology, EarlyView.Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source
SUN-LB047 Two Unusual Cases of Pituitary Tumors Presenting with Acromegaly
, 2019 Shilpa Gurnurkar +2 more
openalex +1 more source
Homo sapiens, industrialisation and the environmental mismatch hypothesis
Biological Reviews, EarlyView.ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
MRI Findings of Causalgia of the Lower Extremity Following Transsphenoidal Resection of Pituitary Tumor [PDF]
, 2012 D. Ryan Ormond +2 more
openalex +1 more source
Exploring Brain Parenchymal Changes in Acromegaly: Focus on White Matter Hyperintensities
Clinical Endocrinology, EarlyView.ABSTRACT Introduction Acromegaly is a rare chronic disease caused by excessive secretion of growth hormone. Even with biochemical control, hormonal imbalance may lead to cerebral changes. This study aimed to evaluate the presence of white matter hyperintensities (WMHs) in patients with acromegaly.
Denise Costa +7 more
wiley +1 more source
Erythropoietin-producing hepatocellular receptor B6 is highly expressed in non-functioning pituitary neuroendocrine tumors and its expression correlates with tumor size [PDF]
Hadara Rubinfeld +7 more
openalex +1 more source