Results 11 to 20 of about 101,852 (311)
Aggressive Pituitary Tumors [PDF]
Pituitary adenomas are common intracranial tumors that are mainly considered as benign. Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of the surrounding tissues, resistance to conventional treatment leading to early and frequent recurrences.
Chatzellis, E. +3 more
openaire +3 more sources
In the pituitary sella, the coexistence of pituitary adenoma and primary pituitary lymphoma is exceedingly rare. Thus far, only six cases have been reported. Here, we present the seventh case of coexisting pituitary adenoma and primary pituitary lymphoma,
Shangjun Ren +6 more
doaj +1 more source
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R. +13 more
core +3 more sources
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta +7 more
core +1 more source
Pituitary adenoma is one common type of intracranial tumors, accounting for about 10% of intracranial tumors. Although pituitary adenomas are benign tumors, the complete resection and recurrence prevention remain challengeable due to aggressive growth of
LEI Ting +5 more
doaj +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
core +1 more source
Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
openaire +2 more sources
Pituitary tumor apoplexy [PDF]
Pituitary tumor apoplexy is a medical emergency due to acute infarction or hemorrhage in the pituitary gland. In this review, the authors discuss the sellar anatomy, the pituitary gland and adenomas' vascularization and the general aspects of the syndrome such as its ethiopatogenesis, predisposing factors, clinical features, treatment and prognosis.
Chang, Claudia V. +4 more
openaire +4 more sources
The fourth edition of the latest classification principles for endocrine tumors was published by the World Health Organization (WHO) in 2017. The latest tumor classification and new pathological classification of each pituitary gland tumor were given in ...
GUAN Hong +4 more
doaj +1 more source
Pituitary tumors and the risk of other malignancies: is the relationship coincidental or causal?
Pituitary adenomas are benign neoplasms of the pituitary. The most prevalent are prolactinomas and non-functioning pituitary adenomas, followed by growth hormone-and ACTH-secreting adenomas.
Sandra Pekic +2 more
doaj +1 more source

