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PATHOGENESIS OF PITUITARY TUMORS

Endocrinology and Metabolism Clinics of North America, 1999
Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or TSH) or may be nonfunctional. Despite their high prevalence in the general population, these tumors are invariably benign and exhibit features of differentiated pituitary cell
openaire   +5 more sources

Pituitary tumors and pregnancy

Growth Hormone & IGF Research, 2003
Tumors vary in how they affect pregnancy depending upon the hormone secreted. Some hormone oversecretion syndromes must be controlled to allow pregnancy to proceed without undue maternal and fetal morbidity (Cushing's disease and hyperthyroidism) whereas treatment during pregnancy for other tumors is not necessary.
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Management of Pituitary Tumors

Neurologic Clinics, 1986
Pituitary adenomas represent the only true adenomas of the cranial cavity. In 1000 asymptomatic pituitary glands examined at autopsy, there was a 22.4 per cent incidence of undetected microadenomas. Advances in diagnostic endocrinology, in radiologic imaging, and in surgical and medical treatments have brought many more patients to the attention of the
Karin Muraszko, Kalmon D. Post
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Angiogenesis and Pituitary Tumors

Seminars in Ophthalmology, 2009
Pituitary adenomas often first manifest through visual symptoms. They are typically slow-growing and histologically benign tumors, but can become clinically destructive, invade adjacent structures, and recur after treatment. Unlike many other tumors that become aggressive and appear to depend upon angiogenesis in the process, pituitary adenomas tend to
Adam B Cohen, Simmons Lessell
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Pituitary tumors in childhood

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
This review focuses on recently published literature on pituitary tumors in children with special focus on craniopharyngioma and prolactinoma. Although most pituitary masses are benign neoplasms, they are associated with high morbidity and mortality related to their proximity to vital neurologic structures including the optic chiasm, hypophysis and ...
Molly H. Harrington, Samuel J. Casella
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Radiotherapy of Pituitary Tumors

Endocrinology and Metabolism Clinics of North America, 1987
The treatment of pituitary adenomas with conventional radiotherapy is safe and effective. Radiation controls the mass effects of large tumors in 80 to 90 per cent of patients and is especially valuable in preventing recurrence after partial resection. In acromegaly, about 80 per cent of patients are controlled; with Cushing's disease, the ultimate cure
Francine Halberg, Glenn E. Sheline
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Pituitary Gland Tumors

2005
Few human pituitary tumor cell lines have been established. This scarcity may be related to the fact that hormone production rapidly declines within weeks to months after initiation of the culture. In addition, the number of proliferating cells in pituitary adenomas is very low.
Steven W. J. Lamberts, Leo J. Hofland
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Immune profiling of pituitary tumors reveals variations in immune infiltration and checkpoint molecule expression

Pituitary, 2021
Yu Mei   +10 more
semanticscholar   +1 more source

Malignant pituitary tumors

Pathology - Research and Practice, 1988
Pituitary malignancies are rare. The definition of pituitary malignancy is still subject to debate. Three types of malignancy with the description of clinical course and complete autopsy were presented; i) true carcinosarcoma, ii) ectopic sphenoid invasive tumor, and iii) post-irradiation sarcoma.
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Pituitary Tumors and Hyperprolactinemia

Archives of Internal Medicine, 1976
Hyperprolactinemia was demonstrated in eight of nine patients with clinical evidence of pituitary tumors without acromegaly or Cushing syndrome. Hourly sampling for 24 hours disclosed elevation of serum prolactin concentrations, whereas, measurable serum growth hormone levels were found rarely.
William B. Malarkey, John C. Johnson
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