Results 151 to 160 of about 33,034 (254)

Long-Term Efficacy and Safety of Glycerol Phenylbutyrate in Japanese Patients With Urea Cycle Disorders: Results From a Phase 3 Switch-Over and 12-Month Extension Study. [PDF]

JIMD Rep
Wada Y, Furujo M, Kashimada K, Hamazaki T, Nyuzuki H, Ichimoto K, Kakiuchi T, Matsumoto S, Watanabe Y, Ono C, Shimizu T, Furukawa H, Nakamura K.   +12 more
europepmc   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Bleeding Risk Assessment and Management Strategies for Elective Surgery and Invasive Procedures: A Systematic Review. [PDF]

Cureus
Alsagga H, Bassiony MI, Eladani OMB, Elhadi Elmana B, Alagha Z, Suliman Y, Ahmed H, Mokhtar AE, Ahmed A.   +8 more
europepmc   +1 more source

Enhanced Monocular Depth Estimation Using ResNet Backbone and Multiscale Feature Decoding for Precise Object Distance Measurement

Advanced Intelligent Systems, EarlyView.
A lightweight monocular perception framework generates high‐fidelity depth maps and integrates YOLOv8 detection to estimate object‐wise distances from a single RGB image. Evaluated on KITTI and the proposed D‐Far250 dataset, the system demonstrates accurate long‐range perception up to 250 m while maintaining real‐time performance, enabling scalable ...
Faseeh Muhammad, Misbah Bibi, Murad Ali Khan, Syed Shehryar Ali Naqvi, Adnan Ejaz Muhammad, Do-Hyeun Kim   +5 more
wiley   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Immunoglobulins: A Systematic Review. [PDF]

Clin Pharmacokinet
van der Zeeuw SL, van Tilburg SJ, Jacobs BC, Koch BCP, Dalm VASH, Crombag MBS, Preijers T.   +6 more
europepmc   +1 more source

How does the Kids SIPsmartER program impact the sugar‐sweetened beverage intake of students: An investigation beyond total treatment effect in randomized controlled trial

American Journal of Agricultural Economics, EarlyView.
Abstract This study develops and empirically estimates a structural framework to decompose the causal pathways of multilevel behavioral interventions targeting adolescent health behaviors. We apply this framework to the Kids SIPsmartER (KSS) program, a 6‐month, school‐based intervention evaluated through a clustered randomized controlled trial in rural
Naveen Abedin, Wen You, Annie Reid, Kathleen Porter, Brittany Kirkpatrick, Jamie Zoellner   +5 more
wiley   +1 more source

Maternal and Pediatric Precision in Therapeutic Knowledge Portal (MPRINT-KP): Landscape Analysis of Pharmacology Research in Maternal and Pediatric Patient Populations. [PDF]

Pharmacotherapy
Liu X, Shendre A, Wang L, O'Kane A, Ma H, Chiang CW, Zaidi SS, Aboshady OA, So G, Tillman EM, Kirkpatrick LM, Costantine M, Grannis S, Rogerson CM, Bartlett C, Rahurkar S, Cheng L, Ouyang J, Wei P, Zhu Z, Li S, Huang Y, Wang L, Cao W, Jiang H, Liu J, Oteng SR, Goodwin A, Deypalubos JAF, Zhang S, Bies R, Quinney SK, Li L.   +32 more
europepmc   +1 more source

Translation and Cross‐Cultural Adaptation of the Chronic Rhinosinusitis Control Test for Global Use

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction The Chronic Rhinosinusitis Control Test (CRCT) is a patient‐reported outcome measure (PROM) written in English that is psychometrically validated to measure chronic rhinosinusitis control. Because the availability of translated PROMs is a driver of data equity—collection of data that is fair and generally representative—our ...
Hye K. Pae, Detong Xia, Hanzhong Sun, Yudi Chen, Kwangoh Yi, Minjeong Song, Eriko Sato, Ali R. Abasi, Jody Ballah, Anna Babarczy, Raymond Bertram, Agnieszka Biernacka, Mable Chan, Teresa Civera, Irina Dubinina, Doğu Erdener, María Isabel Maldonado García, Ali Garib, Tuomo Häikiö, Fuk‐chuen HO, Li‐Yu Hung, R. Malatesha Joshi, Oksana Kanerva, Kiranpreet Kaur Baath, Björn Köhnlein, Dalibor Kučera, Paula Luegi, Yustinus Calvin Gai Mali, Sivan Medina, Stefan Milosavljević, Amna Mirza, Mohamed Y. Mwamzandi, Fatemeh Nami, Anabella‐Gloria Niculescu‐Gorpin, Portia Padilla, Georgia Panayiotou, Manuel Perea, Luciano Perondi, Hiển Phạm, Rasmus Puggaard‐Rode, Anurag Rimzhim, Sreeparna Sarkar, David L. Share, Gláucia V. Silva, Antônio R. M. Simões, Charlotte Stormbom, Titima Suthiwan, Katsuo Tamaoka, Mila Tasseva‐Kurktchieva, Paweł Urbanik, An Van, Katie M. Phillips, Ahmad R. Sedaghat   +52 more
wiley   +1 more source

Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl‐Substituted, α‐Oxidized γ‐Amino Acids

Angewandte Chemie, EarlyView.
Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang, Alexander Popoff, Maja Hunter, Guangzhi Dai, Ronald Garcia, Huixin Xu, Haowen Zhao, Asfandyar Sikandar, Liujie Huo, Rolf Müller, Chengzhang Fu   +10 more
wiley   +2 more sources

Screening chemical libraries for the development of oral treatments for bleeding disorders. [PDF]

Blood Vessel Thromb Hemost
Zelli R, Seyve L, Dagher MC, Navarro R, Barette C, Coradin H, Polack B, Jourdan M, Marlu R, Thomas A.   +9 more
europepmc   +1 more source