Results 81 to 90 of about 33,034 (254)

Current Understanding of Inherited Modifiers of FVIII Pharmacokinetic Variation

Pharmacogenomics and Personalized Medicine, 2023
Laura L Swystun, David Lillicrap Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON, CanadaCorrespondence: David Lillicrap, Richardson Laboratory, Queen’s University, 88 Stuart Street, Kingston, Ontario, K7L 3N6, Canada, Tel
Swystun LL, Lillicrap D
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Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Pyruvate kinase (PK) deficiency in Jordan.

Haematologica, 1993
The clinical and biochemical aspects of two cases of PK deficiency associated with chronic hemolytic anemia in two unrelated patients are reported. The residual erythrocyte PK enzymes in both patients were characterized by the recommended methods of the International Committee for Standardization in Hematology (ICSH).Patient (W.Q.) had 60% residual PK ...
openaire   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

1‐D Collocated Dual‐Gradient Sensory Fibers for Comprehensive Sensing and Decoding of Complex Human Motion and Physiology

Advanced Materials, EarlyView.
Coupled materials design enables a monolithic fiber that integrates complementary sensing regimes into a single wearable strand. By preserving informative signal features across subtle physiological deformation, large body motion, and mixed mechanical inputs, the dual‐gradient architecture generates synchronized, less redundant outputs that improve ...
Yunheum Lee, Sungha Jeon, Min Kim, Joonhee Won, Jinwook Yeo, Kyunghyun Jo, Soyeon Lee, Kieun Park, Yechan Yang, Chul Kim, Gun‐Hee Lee, Seunghwa Ryu, Sungho Jo, Seongjun Park   +13 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

Advanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet, Priyanka Kumari, Sathyanarayana Paladugu, Damian Pociecha, Jakub Karcz, Przemysław Kula, Nataša Vaupotič, Ewa Górecka, Oleg D Lavrentovich   +8 more
wiley   +1 more source

From Pores to Pavement: Advanced Modeling of Aluminosilicates for Scalable Carbon Capture in Concrete

Advanced Science, EarlyView.
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair, Jéssica de O. N. Ribeiro, Murilo Daniel de Mello Innocentini, Kevin Paine, Juliana Calabria‐Holley   +4 more
wiley   +1 more source

Prekallikrein (PK) Tokushima: PK deficiency caused by a Gly401→Glu mutation [PDF]

Journal of Thrombosis and Haemostasis, 2003
T. Shigekiyo, O. Fujino, Y. Kanagawa, T. Matsumoto   +3 more
openaire   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source